Dictamine (2 μg/mL, 200 μL, applied once daily, for 14 days) reduces skin inflammation and skin swellingin Oxazolone (HY-126360)-induced atopic dermatitis mice model[2].
Dictamine (50 and 100 mg/kg, p.o., three times a week) inhibits tumor growth in a HCT116 xenograft tumor model[3].
Dictamine (1 and 5 mg/kg, 200 μL, applied to the skin) ameliorates chronic itch in 2,4-dinitrofluorobenzene-induced atopic dermatitis mice[4].
| Animal Model: | HCT116 xenograft tumor model[3] |
| Dosage: | 50 and 100 mg/kg |
| Administration: | p.o., three times a week |
| Result: | Inhibited tumor growth.
Reduced HIF-1α and Slug protein level in the tumor tissue. |
