GENERAL PROCEDURE: The general method for the synthesis of 4-(pyrrolidin-1-yl)aniline from 1-(4-nitrophenyl)pyrrolidine is as follows: 1-(substituted)4-nitrophenyl derivatives IVa, b, e, f (0.01 mol) were dissolved in NH4OH (20 mL, 30%) and an aqueous solution of sodium conidiosulfite (7 g, 0.04 mol) was quickly added (30 mL). The reaction mixture was refluxed for 15 min. After completion of the reaction, the mixture was cooled and the crude product was obtained by filtration. The crude product was washed and crystallized from dichloromethane to give the target compounds Va, b, e, f. Among them, 4-(pyrrolidin-1-yl)aniline Vb was obtained in 80% yield as a yellow oily substance (in agreement with the literature report) [66].
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