p,p''-DDE-13C12 is a labeled analog of 4,4''-DDE (D195205), which is a metabolite of DDT (D434195), a synthetic organochlorine insecticide that functions by opening sodium ion channels in the insects’ neurons, causing them to fire spontaneously which in turn leads to death. 4,4''-DDE has shown to have endocrine disrupting effects on gonadotropin hormones in pituitary gonadotrope cells.
