2,?6-?Dichloro-?1,?5-?dinitronaphthalene is an intermediate in the synthesis of 1,2,5,6-Tetrachloronaphthalene (T291545), which is a polychlorinated naphthalene (PCN) with dioxin-like toxic properties. It can induce different biochemical changes by activating cellular aryl hydrocarbon receptor (AhR).