地司特泰
地司特泰 性质
| 沸点 | 1968.7±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.327 |
| 储存条件 | Store at -20°C |
| 溶解度 | DMSO：≥ 200 mg/mL (126.52 mM)；水：< 0.1 mg/mL（不溶） |
| 酸度系数(pKa) | 3.15±0.10(Predicted) |
| InChIKey | IUYPEUHIWDMJLM-INGCBPSVNA-N |
地司特泰 用途与合成方法
Disitertide (100 μg/mL) suppresses the protein expression levels of PI3K and p-Akt, and induce the protein expression of Bax in MC3T3-E1 cells.
Disitertide (TGF-β1 inhibitor) abrogates the MACC1- AS1 expression in GC cells, suggesting that targeting TGFβ signaling pathway may be a potential strategy to inhibit MSC-induced stemness and chemoresistance.
Disitertide (P144, 10 μg/mL to 200 μg/mL) affects proliferation, induces apoptosis as well as anoikis in A172 and U-87 MG GBM cell lines.
Western Blot Analysis
| Cell Line: | Mouse embryo osteoblast precursor MC3T3-E1 cells. |
| Concentration: | 100 μg/mL. |
| Incubation Time: | 4 h. |
| Result: | Significantly suppressed the protein expression levels of PI3K and p-Akt, and induce the protein expression of Bax in MC3T3-E1 cells compared with the miR-590 group. |
Disitertide (Topical application, 300 μg/mL) may promote scar maturation and clinical improvement of hypertrophic scar morphology features in an “in vivo” model in nude mice after two weeks of treatment.
| Animal Model: |
Human hypertrophic scars were implanted in 60 nude mice.
|
| Dosage: | 300 μg/mL was added the Lipogel. |
| Administration: | Topical application daily administered. |
| Result: | Successful shedding was achieved in 83,3% of the xenografts. |
地司特泰 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2022-09-18 | HY-P0118 | 地司特泰 | 272105-42-7 | 5mg | 3500 |
| 2022-09-18 | HY-P0118 | 地司特泰 | 272105-42-7 | 10mg | 5600 |
