基本属性 生物活性靶点体外研究体内研究 用途与合成方法 RECILISIB 钠盐 价格(试剂级) 供应商 供应信息

RECILISIB 钠盐

RECILISIB 钠盐

中文名称:RECILISIB 钠盐
英文名称:4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
CAS号:334969-03-8
分子式:C16H13ClO4S
分子量:336.79
EINECS号:
Mol文件:334969-03-8.mol
RECILISIB 钠盐 结构式

RECILISIB 钠盐 性质

沸点 607.8±55.0 °C(Predicted)
密度 1.423±0.06 g/cm3(Predicted)
储存条件 Store at -20°C
溶解度 二甲基亚砜:35.71 mg/mL(106.03 mM)
形态 固体
酸度系数(pKa) 4.00±0.10(Predicted)
颜色 白色至米白色

RECILISIB 钠盐 用途与合成方法

Recilisib 是一种辐射防护剂,可以激活细胞中 AKT 和 PI3K 的活性。

Akt

PI3K

Recilisib Sodium (up to 50 µM) shows a normal distribution of cells throughout the cell cycle, with a slight reduction in the number of cells in S-phase at 50 µM. Continuous exposure of Recilisib Sodium (100 µM) does not result in cell death. Recilisib Sodium does not inhibit the ability of human bone marrow to form colonies in methylcellulose at either timepoint. Recilisib Sodium treatment does not inhibit the colony forming potential of human bone marrow cells. Recilisib Sodium provides dose dependent protection of human bone marrow cells at all three doses of IR. Recilisib Sodium activates the phosphorylation of AKT and GSK3α/β in HFL cells. Recilisib Sodium increases PI3K activity in HFL-1 cells and murine bone marrow cells in response to radiation exposure. Recilisib Sodium treatment in combination with radiation alters the MAPK signaling pathway.

Recilisib Sodium (500 mg/kg) significantly increases the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice. Recilisib Sodium in combination with radiation reduces CFU numbers in mice, but the Recilisib Sodium-treated mice consistently retain a capability to form differentiated colonies. Recilisib Sodium treated mice have a progenitor cell population that is never completely depleted by radiation exposure.

RECILISIB 钠盐 价格(试剂级)

更新日期 产品编号 产品名称 CAS号 包装 价格
2024-11-08 HY-101625 1 mg 500
2024-11-08 HY-101625 RECILISIB 钠盐 334969-03-8 5mg 1100

RECILISIB 钠盐供应商 更多

武汉壹加壹生物科技有限公司
现货
联系电话:027-027-16602739303 16602739303
产品介绍:
中文名称:RECILISIB 钠盐
英文名称:Recilisib sodium
CAS:334969-03-8
纯度:95%,98%
包装信息:5G
库存量:1g,kg
现货日期:2024/12/12 9:51:20
北京普西唐生物科技有限公司
联系电话:010-60605840 18892239720
产品介绍:
英文名称:Recilisib sodium(ON01210)
CAS:334969-03-8
纯度:98%(HPLC)
包装信息:5mg;1mg
上海与昂生物科技有限公司
联系电话:021-58111628 15800915896
产品介绍:
英文名称:Recilisib sodium
CAS:334969-03-8
纯度:98%+
包装信息:1g;5g;10g
深圳聚合生化科技有限公司
联系电话:+86-400-002-6226 +86-13028896684;
产品介绍:
英文名称:4-[(1E)-2-[[(4-CHLOROPHENYL)METHYL]SULFONYL]ETHENYL]-BENZOIC ACID
CAS:334969-03-8
纯度:95%+
备注:mg\g\kg\ton
上海源溪生物科技有限公司
联系电话:021-58447131 13564518121
产品介绍:
中文名称:RECILISIB 钠盐
英文名称:Recilisib
CAS:334969-03-8
纯度:98% HPLC
包装信息:100mg,250mg,1g

最新发布供应信息

RECILISIB 钠盐|T13862|TargetMol
TargetMol中国(陶术生物) 2024-12-12