Taurodehydrocholic acid is a biliary cholesterol secretion activator. Taurodehydrocholic acid significantly increases the expression of Abcg5 and decreases the expression of abc8. Taurodehydrocholic acid can be used in the study of cholesterol metabolism[1].
ChEBI: Taurodehydrocholic acid is a bile acid taurine conjugate.
[1] Hismiogullari A A, et al. Effect of Taurodehydrocholic Acid on the Hepatic Expression of Abcg5 and Abcg8 and Biliary Parameters in the Fistula Rat[J]. Acta Medica Mediterranea, 2018, 34: 33-38.