3-(2,4-dimethoxybenzylidene)anabaseine

Chemical Properties

Melting point	216-217℃ (decomposition)
storage temp.	2-8°C
solubility	H2O: >5mg/mL
form	powder
color	faint yellow to dark yellow
Water Solubility	H2O: >5mg/mL
InChI	1S/C19H20N2O2.2ClH/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16;;/h3,6-9,11-13H,4-5,10H2,1-2H3;2*1H/b15-11+;;
InChIKey	RPYWXZCFYPVCNQ-RVDMUPIBSA-N
SMILES	Cl.Cl.COc1ccc(\C=C2/CCCN=C2c3cccnc3)c(OC)c1

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Animal Model:	C57BL6 mice were irradiated with 12 Gy to induce a mouse model of Radiation induced lung injury (RILI)^[3]
Dosage:	4 mg/kg
Administration:	I.p.; 1, 3, 7, 14 and 21 days
Result:	Reduces lung inflammatory infiltrate and fibrosis in radiation treated mice.