≥28.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form
Powder
pka
12.94±0.70(Predicted)
color
Off-white to yellow
Description
THZ1 is a covalent cyclin-dependent kinases 7 (CDK7) inhibitor. It has the ability to target a remote cysteine residue located outside of the canonical kinase domain, providing a means of achieving selectivity for CDK7.
