Selexipag

$28 - $5460

Product nameSelexipag
Cas No475086-01-2
MFC26H32N4O4S
MW496.62
MDL NumberMFCD10567093

Synonyms

NS-304;ACT-293987;NS-304(Selexipag);Selexipag API;2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-ylaMino]butoxy]-N-MethylsulfonylacetaMide;AcetaMide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-Methylethyl)aMino]butoxy]-N- (Methylsulfonyl)-;Selexipag intermediate 1;2-[4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy]-N-(methylsulfonyl)acetamide

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Price

61 prices

Brand less more

TCI Chemical Sigma-Aldrich Cayman Chemical Arctom Chemenu Crysdot AccelPharmtech Tocris TRC ApexBio Technology Matrix Scientific Axon Medchem ChemScene Biosynth DC Chemicals
Package less more

50 1mg 2mg 5mg 10mg 25mg 50.00mg 50mg 100mg 100.00mg 250mg 250.00mg 1g 10mm*1mlindmso(solution) 10mm*1mlindmso(solid+solvent) 5g 100g 10 25g

Clear All Done

Brand	Packaging	Price	Product name
AccelPharmtech XP1293	5G	$420	Selexipag
AccelPharmtech XP1293	5G	$420	Selexipag
AccelPharmtech XP1293	25G	$1560	Selexipag
AccelPharmtech XP1293	25G	$1560	Selexipag
AccelPharmtech XP1293	100G	$5460	Selexipag
AccelPharmtech XP1293	100G	$5460	Selexipag
ApexBio Technology B7378	5mg	$77	NS 304
ApexBio Technology B7378	2mg	$110	NS304
ApexBio Technology B7378	10mg	$129	NS 304
ApexBio Technology B7378	50mg	$311	NS 304

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Properties

Melting point	134-138°C
Density	1.210±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.82±0.40(Predicted)
form	Solid
color	Pale Yellow
InChIKey	QXWZQTURMXZVHJ-UHFFFAOYSA-N
SMILES	C(NS(C)(=O)=O)(=O)COCCCCN(C1=NC(C2=CC=CC=C2)=C(C2=CC=CC=C2)N=C1)C(C)C

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H315：Causes skin irritation

H319：Causes serious eye irritation

Precautionary statements

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313：IF SKIN irritation occurs: Get medical advice/attention.

P337+P313：IF eye irritation persists: Get medical advice/attention.

Description

NS-304 is a potent vasorelaxant and inhibitor of human platelet aggregation that mediates its actions by binding to a specific G protein-coupled receptor, the IP receptor, on the surface of platelets and endothelial cells.The IP receptor also participates in signal transduction of the cardioprotection, inflammation and pain response. NS-304 is a prodrug of the active form of MRE-269, which is a potent and selective agonist for the human IP receptor with a Ki value of 20 nM. In contrast to PGI2, which has a half-life of 30 seconds to several minutes in vivo, NS-304 is long-acting. Plasma concentrations of MRE-269 remain near peak levels for more than eight hours in rats and dogs after NS-304 was administered orally.

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Suppliers and manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

$0.00/1g

Selexipag

CAS:475086-01-2
career henan chemical co

$2.00/1KG

Selexipag

CAS:475086-01-2
Seasons Biotechnology Co., Ltd.
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.
Protheragen-ING
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Beijing Yibai Biotechnology Co., Ltd

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