PricePropertiesSafety InformationDescription
ChemicalBook > CAS DataBase List > Rotenone

Rotenone

  • $20.8 - $570
  • Product name:Rotenone
  • CAS:83-79-4
  • MF: C23H22O6
  • MW:394.41718
  • EINECS:201-501-9
  • MDL Number:MFCD00005096
  • Synonyms:Rotenone(Barbasco);(-)-cis-rotenone ;(1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aalphaH)-one, 1,2,12,12aalpha-tetrahydro-2alpha-isopropenyl-8,9-dimethoxy-;(1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-alpha-iospropenyl-8,9-dimethoxy-;(1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-2-alpha-isopropenyl-8,9-dimethoxy-;(1)benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6alphah)-one,1,2,12,12aalpha-t ;(2r-(2alpha,6aalpha,12aalpha))--9-dimethoxy-2-(1-methylethenyl)- ;(2R,2alpha,6aalpha,12aalpha)-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one
Price
  • Brand:Sigma-Aldrich
  • Product number:R8875
  • Product nameRotenone
  • Purity:≥95%
  • Packaging:1g
  • Price:$85.1
  • Updated:2019/12/2 14:10:03
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:557368
  • Product nameRotenone
  • Purity:
  • Packaging:1gm
  • Price:$86
  • Updated:2019/12/2 14:10:03
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:45656
  • Product nameRotenone
  • Purity:PESTANAL , analytical standard
  • Packaging:250mg
  • Price:$20.8
  • Updated:2019/12/2 14:10:03
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:R8875
  • Product nameRotenone
  • Purity:≥95%
  • Packaging:5g
  • Price:$261
  • Updated:2019/12/2 14:10:03
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:R8875
  • Product nameRotenone
  • Purity:≥95%
  • Packaging:10g
  • Price:$397
  • Updated:2019/12/2 14:10:03
  • Buy:Buy
Properties
  • Melting point:159-164 °C(lit.)
  • alpha -115 º (C=1.4 IN CHLOROFORM)
  • Boiling point:210-220 °C0.5 mm Hg(lit.)
  • Density 1.1917 (rough estimate)
  • refractive index 1.4593 (estimate)
  • storage temp. Store at RT
  • Water Solubility 15 mg l-1 (100 °C)
  • form White to off-white solid
  • Merck 14,8271
  • BRN 6773081
  • Stability:Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, especially in the presence of alkalies.
  • InChIKeyJUVIOZPCNVVQFO-HBGVWJBISA-N
  • NIST Chemistry ReferenceRotenone(83-79-4)
  • EPA Substance Registry SystemRotenone (83-79-4)
Safety Information
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements
  • H301:Toxic if swalloed
  • H315:Causes skin irritation
  • H319:Causes serious eye irritation
  • H335:May cause respiratory irritation
  • H410:Very toxic to aquatic life with long lasting effects
  • Precautionary statements
  • P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P273:Avoid release to the environment.
  • P280:Wear protective gloves/protective clothing/eye protection/face protection.
  • P391:Collect spillage. Hazardous to the aquatic environment
  • P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
  • P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
  • P337+P313:IF eye irritation persists: Get medical advice/attention.
  • P501:Dispose of contents/container to..…

Description

Rotenone is a classical inhibitor of complex I of the mitochondrial electron transport chain, inhibiting NADH/DB oxidoreductase and NADH oxidase with IC50 values of 28.8 and 5.1 nM, respectively. In animals, it drives neurodegeneration, resulting in features similar to some behavioral and neuropathological aspects of Parkinson’s disease. This naturally-occurring isoflavonoid is commonly used as an insecticide, piscicide, and pesticide.


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