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ChemicalBook CAS DataBase List Oxaliplatin

Oxaliplatin

$19 - $2107

Product nameOxaliplatin
Cas No61825-94-3
MFC8H12N2O4Pt
MW395.28
EINECS621-248-1
MDL NumberMFCD00866327

Synonyms

[SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM;OXALIPLATIN;trans-l-diaminocyclohexane oxalatoplatinum;(1,2-cyclohexanediamine-n,n’)(ethanedioato(2-)-o,o’)-platinu(sp-4-2-(1r-tr ;oxalato(1r,2r-cyclohexanediammine)platinum(ii) ;oxalatoplatin ;[SP-4-2-(1R-trans)]-(1，2-Cyclohexanediamine-N，N，)[ethanedioato(2-)-O，O’Jplatinum;NSC-266046：Elocatin

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TCI Chemical Sigma-Aldrich Cayman Chemical CSNpharm JR MediChem Arctom Crysdot AvaChem Tocris TRC Usbiological Biorbyt Ltd ApexBio Technology Matrix Scientific AK Scientific Adipogen Life Sciences Medical Isotopes, Inc. Chem-Impex BroadPharm ChemScene Biosynth Carbosynth DC Chemicals
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Brand	Packaging	Price	Product name
Adipogen Life Sciences AG-CR1-3592-M005	5mg	$20	Oxaliplatin
AK Scientific J50808	10g	$795	Oxaliplatin
AK Scientific H874	25g	$2107	Oxaliplatin
ApexBio Technology A8648	200mg	$145	Oxaliplatin
Arctom AS027937	1g	$129	Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II)
Arctom AS027937	100mg	$31	Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II)
Arctom AS027937	250mg	$38	Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II)
Arctom AS027937	50mg	$19	Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II)
Arctom AS027937	25g	$1960	Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II)
Arctom AS027937	5g	$534	Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II)

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Properties

alpha	+74.5-78.0 (D/20)(c=0.5,H2O)
storage temp.	2-8°C
solubility	Slightly soluble in water, very slightly soluble in methanol, practically insoluble in anhydrous ethanol.
form	solid
color	White to Almost white
Water Solubility	Soluble in water with heating and/or sonication
Merck	14,6912
Stability	Stable. Store cool. Incompatible with oxidizing agents.
InChI	InChI=1/C6H12N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-8H,1-4H2;(H,3,4)(H,5,6);/q-2;;+4/p-2/t5-,6-;;/s3
InChIKey	ZROHGHOFXNOHSO-BNTLRKBRSA-L
SMILES	O=C1C([O-][Pt+2]2(N[C@]3([H])CCCC[C@@]3([H])N2)[O-]1)=O \|&1:6,12,r\|
CAS DataBase Reference	61825-94-3

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H315：Causes skin irritation

H317：May cause an allergic skin reaction

H319：Causes serious eye irritation

H335：May cause respiratory irritation

H340：May cause genetic defects

Precautionary statements

P202：Do not handle until all safety precautions have been read and understood.

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313：IF exposed or concerned: Get medical advice/attention.

Description

Oxaliplatin is a platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells, preventing DNA replication and transcription which leads to cell death. Oxaliplatin has cytotoxic effects in a broad range of cell lines, including colon, ovarian, and lung cancer, with IC50 values ranging from 0.5-240, 0.12-19.8, and 2.6-6.1 μM, respectively. Through its general cytotoxic effects, oxaliplatin has anti-tumor activity against advanced colorectal cancer and is typically administered with fluorouracil and leucovorin in a combination known as FOLFOX.

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Suppliers and manufacturers

SHANDONG BOYUAN PHARMACEUTICAL CO., LTD.

$0.00/1000g

Oxaliplatin

CAS:61825-94-3
Hebei Chuanghai Biotechnology Co., Ltd

$10.00/1KG

Oxaliplatin

CAS:61825-94-3
Shaanxi Dideu Medichem Co. Ltd

$1.00/1KG

Oxaliplatin

CAS:61825-94-3
Hebei Yanxi Chemical Co., Ltd.

$0.00/1kg

oxaliplatin

CAS:61825-94-3
Hebei Zhuanglai Chemical Trading Co.,Ltd

$95.00/25kg

Oxaliplatin

CAS:61825-94-3
Shaanxi Xianhe Biotech Co., Ltd

$0.00/1kg

Oxaliplatin

CAS:61825-94-3
Sinoway Industrial co., ltd.

$0.00/25KG

Oxaliplatin

CAS:61825-94-3
Henan Tianfu Chemical Co.,Ltd.
Nanjing Finetech Chemical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED

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