Nitrendipine is a dihydropyridine used as an antihypertensive agent due to its ability to block L-type and T-type calcium channels, which play key roles in excitation-contraction coupling in cardiac and vascular smooth muscle cells, producing vasodilatory actions. It also binds to adenosine A1, A2A, and A3 receptors with Ki values of 8.96, 23.0, and 8.3 μM, respectively.
