MK-2 Inhibitor III

$73 - $2000

Product nameMK-2 Inhibitor III
Cas No1186648-22-5
MFC21H18N4O2
MW358.4

Synonyms

MK-2 Inhibitor III;2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one:hydrate;MK-2 INHIBITOR III (COMPOUND 16);MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem;MK2-IN-3 hydrate;2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate;Inhibitor,MAP kinase activated protein kinase 2,inhibit,MK2 IN 3 hydrate,MAPKAP kinase 2,MK-2-IN-3 hydrate,MAPK activated protein kinase 2,MK2IN3 hydrate,MAPKAPK2 (MK2),Mitogen-activated protein kinase activated protein kinase 2

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Price

7 prices

Brand less more

Cayman Chemical AK Scientific Medical Isotopes, Inc.
Package less more

500μg 1mg 2.5mg 5mg 25mg

Clear All Done

Brand	Packaging	Price	Product name
AK Scientific 3003DC	1mg	$220	MK-2InhibitorIII
AK Scientific 3003DC	5mg	$348	MK-2InhibitorIII
Cayman Chemical 15943	5mg	$225	MK2 Inhibitor III
Cayman Chemical 15943	500μg	$73	MK2 Inhibitor III
Cayman Chemical 15943	1mg	$110	MK2 Inhibitor III
Medical Isotopes, Inc. 47746	2.5mg	$625	MK2InhibitorIII
Medical Isotopes, Inc. 47746	25mg	$2000	MK2InhibitorIII

Properties

Melting point	>255°C (dec.)
storage temp.	+2C to +8C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Pale yellow solid
color	Off-White to Pale Yellow

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H315：Causes skin irritation

H319：Causes serious eye irritation

Precautionary statements

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313：IF SKIN irritation occurs: Get medical advice/attention.

P337+P313：IF eye irritation persists: Get medical advice/attention.

Description

MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It less potently blocks MK3 and MK5 (IC50s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC50 = 4.4 μM).

Suppliers and manufacturers

TargetMol Chemicals Inc.

$48.00/1mg

MK2-IN-3 hydrate

CAS:1186648-22-5
TargetMol Chemicals Inc.

$48.00/1mg

MK2-IN-3 hydrate

CAS:1186648-22-5
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Hangzhou MolCore BioPharmatech Co.,Ltd.
Aladdin Scientific
Tianjin Kailiqi Biotechnology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Shanghai Hongye Biotechnology Co. Ltd
Fan De(Beijing) Biotechnology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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