≥40.7 mg/mL in EtOH; ≥40.7 mg/mL in H2O; ≥42.2 mg/mL in DMSO
form
solid
pka
9.97±0.15(Predicted)
color
White
Water Solubility
Soluble in water (4 mM)
Sequence
H-Tyr-D-Ala-Gly-NMe-Phe-Gly-ol
Stability
Hygroscopic
Description
DAMGO is an opioid receptor agonist (1,2). DAMGO can be used to investigate the analgesic mechanism of opioids. It has been shown that DAMGO can modulate the two-pore domain K(+) channels in the substantia gelatinosa neurons (3).