COTI-2;COTI-2;COTI 2;COTI2;1-Piperazinecarbothioic acid, 4-(2-pyridinyl)-, 2-(6,7-dihydro-8(5H)-quinolinylidene)hydrazide;N'-(6,7-Dihydroquinolin-8(5H)-ylidene)-4-(pyridin-2-yl)piperazine-1-carbothiohydrazide;inhibit,Inhibitor,HNSCC,low,anti-cancer,anti-proliferative,toxicity,TNBC,COTI-2,MDM-2/p53,Apoptosis,orally;COTI-2, 10 mM in DMSO
COTI 2, efficiently inhibits the proliferation rate of all the tested cell lines following 72 h of treatment. COTI-2 is significantly effective at inhibiting tumor cell proliferation in all three cell lines (COLO-205, HCT-15, and SW620).
