Ac-LEVD-CHO is a caspase-4 inhibitor.1 It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Ac-LEVD-CHO (10 μM) also reduces apoptosis induced by expression of the dominant negative adenoviral RNA-dependent protein kinase (Ad-Δ6PKR) in A549 and PC3 cancer cells.2WARNING This product is not for human or veterinary use.
