Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO (Item No. 10017), a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF.1,2,3 It is an inhibitor of caspase-3 that reduces caspase-3 activity and apoptosis induced by prostaglandin E2 (PGE2; Item No. 14010) in rat cortical neurons when used at concentrations ranging from 1 to 2.5 μM.4WARNING This product is not for human or veterinary use.
