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ChemicalBook > CAS DataBase List > (-)-Arctigenin

(-)-Arctigenin

  • $49 - $331
  • Product name:(-)-Arctigenin
  • CAS:7770-78-7
  • MF: C21H24O6
  • MW:372.41
  • EINECS:
  • MDL Number:MFCD00870597
  • Synonyms:(3R,4R)-4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-2(3H)-FURANONE;2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL];ARCTIGENIN:2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-Furanone,4-[(3,4-dimethoxyphenyl) methyl];dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-,(3R,4R)-;(-)-ARCTIGENIN;ARCTIGENIN
Price
  • Brand:Cayman Chemical
  • Product number:14913
  • Product nameArctigenin
  • Purity:≥95%
  • Packaging:100mg
  • Price:$245
  • Updated:2021/3/22 16:44:55
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:PHL80354
  • Product nameArctigenin
  • Purity:phyproof Reference Substance
  • Packaging:10mg
  • Price:$290
  • Updated:2021/3/22 19:32:44
  • Buy:Buy
  • Brand:Sigma-Aldrich
  • Product number:SMB00075
  • Product name(?)-Arctigenin
  • Purity:≥95% (LC/MS-ELSD)
  • Packaging:1mg
  • Price:$235
  • Updated:2020/8/18 13:37:41
  • Buy:Buy
  • Brand:TCI Chemical
  • Product number:A3117
  • Product name(-)-Arctigenin
  • Purity:>95.0%(GC)
  • Packaging:10mg
  • Price:$111
  • Updated:2021/3/22 18:33:11
  • Buy:Buy
  • Brand:TCI Chemical
  • Product number:A3117
  • Product name(-)-Arctigenin
  • Purity:>95.0%(GC)
  • Packaging:50mg
  • Price:$331
  • Updated:2021/3/22 18:33:10
  • Buy:Buy
Properties
  • Melting point:98.0 to 102.0 °C
  • Boiling point:567.0±45.0 °C(Predicted)
  • Density 1.227±0.06 g/cm3(Predicted)
  • storage temp. Sealed in dry,Store in freezer, under -20°C
  • solubility DMSO: 34 mg/mL with heating and sonicating, soluble
  • form solid
  • pka10.03±0.20(Predicted)
  • λmax280nm(EtOH)(lit.)
  • InChIKeyNQWVSMVXKMHKTF-JKSUJKDBSA-N
  • CAS DataBase Reference7770-78-7(CAS DataBase Reference)
Safety Information
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Description

Arctigenin is an extract from A. lappa, a burdock plant traditionally used in Japanese Kampo medicine for its antioxidant, anti-inflammatory, antiproliferative, and antiviral activity. At 0.1 μM, arctigenin can block the activation of Akt induced by glucose starvation in pancreatic cancer PANC-1 cells, which is a key process in the tolerance exhibited by cancer cells to glucose starvation. It has potent in vitro antiviral activities against in?uenza A virus and shows neuroprotective effects against an experimental mouse model of Japanese encephalitis. Arctigenin also demonstrates a therapeutic effect in ischemic stroke treatment of middle cerebral artery occluded rats by suppressing microglia activation and decreasing IL-1β and TNF-α expression.


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