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N-Boc-trans-4-Hydroxy-L-proline methyl ester
N-Boc-trans-4-Hydroxy-L-proline methyl ester
$5 - $1195.43
Product name
N-Boc-trans-4-Hydroxy-L-proline methyl ester
Cas No
74844-91-0
MF
C11H19NO5
MW
245.27
EINECS
616-143-2
MDL Number
MFCD00076981
Synonyms
N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER;N-(TERT-BUTOXYCARBONYL)-TRANS-HYDROXYL-L-PROLINE METHYL ESTER;N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE METHYL ESTER;N-BOC-TRANS-4-HYDROXYL-L-PROLINE METHYL ESTER;N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER;N-BOC-L-TRANS-4-HYDROXY-PROLINE METHYL ESTER;(2R,4R)-4-HYDROXY-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER;(2S,4R)-1-(TERT-BUTOXYCARBONYL)-2-CARBOMETHOXY-4-HYDROXYPYRROLIDINE
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Alfa Aesar
TCI Chemical
Sigma-Aldrich
Acrotein
Crysdot
Anichem
TRC
Frontier Specialty Chemicals
Matrix Scientific
AK Scientific
Medical Isotopes, Inc.
Chem-Impex
Apolloscientific
ChemScene
SynQuest Laboratories
ChemPep
American Custom Chemicals Corporation
Biosynth Carbosynth
Ambeed
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Product name
Acrotein
A-5440
250g
$168.85
Boc-trans-4-hydroxy-L-prolinemethylester
AK Scientific
J91745
5g
$10
Boc-trans-4-Hydroxy-L-prolinemethylester
Alfa Aesar
H59027
1g
$30.65
N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%
Alfa Aesar
H59027
5g
$99.65
N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%
Ambeed
A219851
500g
$94
Boc-Hyp-OMe
Ambeed
A219851
100g
$20
Boc-Hyp-OMe
Ambeed
A219851
5g
$5
Boc-Hyp-OMe
Ambeed
A219851
10g
$6
Boc-Hyp-OMe
Ambeed
A219851
25g
$8
Boc-Hyp-OMe
American Custom Chemicals Corporation
AAA0001695
1G
$769.65
N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER
1
of
5
Properties
Melting point
92-96 °C (lit.)
alpha
-65 º (c=1 CHCl3)
Boiling point
132°C/0.05mmHg(lit.)
Density
1.216±0.06 g/cm3(Predicted)
storage temp.
Keep in dark place,Sealed in dry,Room Temperature
solubility
Soluble in chloroform, dichloromethane and ethyl acetate.
form
Crystalline Powder
pka
14.27±0.40(Predicted)
color
White to light beige
optical activity
[α]20/D -65°, c = 1% in chloroform
InChI
InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
InChIKey
MZMNEDXVUJLQAF-SFYZADRCSA-N
SMILES
N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@H]1C(OC)=O
LogP
0.813 at 25℃
CAS DataBase Reference
74844-91-0(CAS DataBase Reference)
Safety Information
Symbol(GHS)
Signal word
Danger
Hazard statements
H314:
Causes severe skin burns and eye damage
Precautionary statements
P260:
Do not breathe dust/fume/gas/mist/vapours/spray.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331:
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353:
IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
Description
It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.
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$5-400
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$5-3740
Suppliers and manufacturers
Hebei Yanxi Chemical Co., Ltd.
$1.00
/1000kg
N-Boc-trans-4-Hydroxy-L-proline methyl ester
CAS:74844-91-0
Hebei Weibang Biotechnology Co., Ltd
$10.00
/100KG
N-Boc-trans-4-Hydroxy-L-proline methyl ester
CAS:74844-91-0
Henan Fengda Chemical Co., Ltd
$1.00
/100KG
N-Boc-trans-4-Hydroxy-L-proline methyl ester
CAS:74844-91-0
PRISUN PHARMATECH CO.,LTD
Zepeptide Biotechnology (Shijiazhuang) Co., Ltd
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Taizhou Tianhong Biochemistry Technology Co., Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
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N-Boc-trans-4-amino-L-proline methyl ester hydrochloride
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N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER
74844-91-0
BOC-HYP-OTBU
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