PIPPS is a zwitterionic non-metal complexing buffer.
Piperazine-N,N′-bis(3-propanesulfonic Acid)
A non-metal complexing, zwitterionic buffer with mixed-mode dissociation constants of pKa1 = 3.73 and pKa2 = 7.96 (100 mM, 25°C) PIPPS has no interference at wavelengths longer than 240 nm.