5-Methoxy-alpha-methyltryptamine

5-methoxy AMT (5-MeO AMT) is a potent psychoactive analog of 5-methoxy DiPT and α-methyltryptamine (AMT), tryptamine derivatives that inhibit reuptake and stimulate release of monoamines. 5-MeO AMT inhibits re-uptake (IC50s = 0.18, 2.9, and 3.37 μM) and stimulates release (EC50s = 1.5, 460, and 8.9 μM) of dopamine, serotonin, and norepinephrine, respectively from rat brain synaptosomes. 5-MeO AMT, sometimes called Alpha-O, has been sold under the guise of LSD and abused as a recreational drug. This tryptamine analog is intended only to be used to aid the forensic analysis of samples that may contain this compound or for scientific research applications.