클로로디메틸페니실란

한글명:클로로디메틸페니실란

카스 번호1833-51-8

상품명:CHLOROMETHYLDIMETHYLPHENYLSILANE

CBNumberCB9344055

분자식C9H13ClSi

포뮬러 무게184.74

MOL 파일1833-51-8.mol

동의어(한글)

(클로로메틸)다이메틸페닐실레인

클로로디메틸페니실란

화학적 성질

끓는 점	106-107 °C/15 mmHg (lit.)
밀도	1.024 g/mL at 25 °C (lit.)
굴절률	n20/D 1.520(lit.)
인화점	196 °F
저장 조건	2-8°C
물리적 상태	투명한 액체
색상	무색 내지 거의 무색
Specific Gravity	1.031
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions
BRN	2935991
CAS 데이터베이스	1833-51-8(CAS DataBase Reference)
EPA	Silane, (chloromethyl)dimethylphenyl- (1833-51-8)

위험 및 안전 성명

위험품 표기

위험 카페고리 넘버

36/37/38

안전지침서

26-36-26/36

유엔번호(UN No.)

1993

WGK 독일

TSCA

Yes

HS 번호

29319000

NFPA 704:

	2
2		0

그림문자(GHS)

클로로디메틸페니실란 화학적 특성, 용도, 생산

물리적 성질
bp 106–107°C/15 mmHg; d 1.024 g cm?3
용도
The first reported preparation and use of (chloromethyl)dimethylphenylsilane was in 1949.At the time, the main utility of (chloromethyl)dimethylphenylsilane was as the starting material for conversion to the corresponding Grignard reagent (see below). Since then, it has also been used for heteroatom alkylation, carbon alkylation, and conversion to a variety of organometallic and organolanthanide reagents. The main advantage of this reagent over the closely related (chloromethyl)trimethylsilane is the ability of (chloromethyl)dimethylphenylsilane to undergo a Fleming oxidation, thus allowing (chloromethyl)dimethylphenylsilane to serve as a masked hydroxyl group. This utility has been exploited for both the C-substituted and Nsubstituted adducts. A major disadvantage of the use of (chloromethyl)dimethylphenylsilane is its propensity to undergo rearrangements under a variety of conditions (see below). (Chloromethyl) dimethylphenylsilane is used as the precursor for the preparation of (phenyldimethylsilyl)methoxymethyl chloride (SMOM-Cl), a hydroxyl protecting group.
(Chloromethyl)dimethylphenylsilane (1) can be utilized to install a silylmethyl group on carbon via base promoted C-alkylation of terminal alkynes,dihydropyrazines,malonic esters,phenylacetonitriles,sulfoxides,and imines.Although has been used directly in the alkylation, conversion to the corresponding iodide via Finkelstein displacement (eq 1) prior to alkylation is sometimeswarranted. Except for the malonic esters (eq 2), strongly basic conditions and lowtemperatures (with slow warming) are generally employed in the transformation (eqs 3 and 4).
제조 방법
can be prepared either by the reaction of phenylmagnesium bromide with chloro(chloromethyl)dimethylsilane in ether at reflux,or by the reaction of phenylmagnesium bromide with chloro(chloromethyl)dimethylsilane in the presence of catalytic (N,N,N,N-tetramethylethylenediamine) zinc in 1,4-dioxane at 20°C.

클로로디메틸페니실란 공급 업체

클로로디메틸페니실란 관련 검색

Send Inquriy