칼시트리올-d6

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Danger

• 유해·위험 문구

  H225：고인화성 액체 및 증기

  H319：눈에 심한 자극을 일으킴

• 예방조치문구

  P210：열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

칼시트리올-d6 화학적 특성, 용도, 생산

• 개요

  Calcitriol-d6 is intended for us as an internal standard for the quantification of calcitriol by GC- or LC-MS. Calcitriol is synthesized from 7-dehydro cholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin. Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy vitamin D₃, the principal circulating form of vitamin D. A second, tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors. The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium, and to increase the mineralization of bone via the direct stimulation of osteoblasts.

• 화학적 성질

  Off-White to Pale Yellow Solid

• 용도

  The biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic

• 일반 설명

  1α,25-Dihydroxyvitamin D3?[1,25(OH)₂D₃], also known as calcitriol, plays a role in calcium and phosphate metabolism in humans. It also regulates insulin secretion and induces cellular differentiation.
  1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d₆?is a deuterated vitamin D3 wherein C-26 and C-27 carbon methyl protons are replaced by deuterium.

칼시트리올-d6 공급 업체

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