베타-NADPH테트라소듐소금

한글명:베타-NADPH테트라소듐소금

카스 번호2646-71-1

상품명:Nadph tetrasodium salt

CBNumberCB7365362

분자식C21H31N7NaO17P3

포뮬러 무게769.42

MOL 파일2646-71-1.mol

동의어(한글)

베타-NADPH테트라소듐소금

화학적 성질

녹는점	>250°C (dec.)
저장 조건	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도	10mM NaOH: 용해성50mg/mL, 투명
물리적 상태	가루
색상	흰색에서 황백색까지
수용성	물에 용해됩니다(50mg/ml).
감도	Light Sensitive
최대 파장(λmax)	260 and 340 nm
Merck	14,6348
InChIKey	ZQJHSLJFGRIJQN-LRANKJFRNA-N

위험 및 안전 성명

위험품 표기	Xi,F
위험 카페고리 넘버	36/37/38-11
안전지침서	26-36/37
WGK 독일	3
F 고인화성물질	3-10-23
HS 번호	29349990

그림문자(GHS)

베타-NADPH테트라소듐소금 화학적 특성, 용도, 생산

개요
NADPH is the reduced form of the coenzyme NADP+; used in anabolic reactions such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.
NADPH, Tetrasodium Salt is a A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.
화학적 성질
off-white to light yellow powder
용도
One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2’position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydroge nases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions.
주요 응용
NADPH is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. In plants, NADPH is produced by ferredoxin-NADP+ reductase in the last step of the electron chain during photosynthesis. In animals is it predominantly produced by the pentose phosphate pathway, but is also generated by key mitochondrial enzymes. NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species.It is also used for the synthesis of lipids and cholesterol and during the process of fatty acid chain elongation.
일반 설명
A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP⁺. The following biological pathways involve NADPH: formation of carbohydrate from CO₂ during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.
생물학적 활성
NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).
Purification Methods
Purification is mostly similar to that of NADH above. [Beilstein 26 III/IV 3671.]

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