글루테티미드
한글명:글루테티미드
카스 번호77-21-4
상품명:DL-Glutethimide
CBNumberCB6399670
분자식C13H15NO2
포뮬러 무게217.26
MOL 파일77-21-4.mol
동의어(한글)
글루테티미드
글루테티미드및그염류
화학적 성질
| 녹는점 | 84°C |
| 끓는 점 | 357.82°C (rough estimate) |
| 밀도 | 1.0960 (rough estimate) |
| 굴절률 | 1.5300 (estimate) |
| 인화점 | 9℃ |
| 저장 조건 | -20°C |
| 용해도 | 클로로포름(약간 용해됨), 메탄올(약간 용해됨) |
| 물리적 상태 | 고체 |
| 물리적 상태 | 단단한 모양 |
| 산도 계수 (pKa) | pKa 11.8 (Uncertain) |
| 색상 | 미색부터 밝은 베이지까지 |
| 수용성 | 0.95g/L(27℃) |
| CAS 데이터베이스 | 77-21-4(CAS DataBase Reference) |
| NIST | Glutethimide(77-21-4) |
| 위험품 표기 | Xn,T,F |
| 위험 카페고리 넘버 | 22-39/23/24/25-23/24/25-11 |
| 안전지침서 | 36-45-36/37-16-7 |
| 유엔번호(UN No.) | 3249 |
| WGK 독일 | 1 |
| RTECS 번호 | MA4725000 |
| 위험 등급 | 6.1(b) |
| 포장분류 | III |
| HS 번호 | 29251200 |
| 유해 물질 데이터 | 77-21-4(Hazardous Substances Data) |
| 독성 | Glutethimide, and a structurally similar compound methyprylon, has been used occasionally as a sedative-hypnotic, although glutethimide’s use for longer than 3 days is not recommended and it is rarely, if ever, prescribed today. Glutethimide causes a skin rash in nearly 10% of those using it, and although it was once thought to produce less respiratory depression than the barbiturates its overdose fatality record is not good. Much of the drug’s action can be attributed to 4-hydroxyglutethimide, which is more than twice as potent and has a long half-life. Like many other sedativehypnotics, abrupt withdrawal after chronic use or abuse resembles that of ethanol or the barbiturates and must be managed accordingly. |
