브로디파쿰

한글명:브로디파쿰

카스 번호56073-10-0

상품명:Brodifacoum

CBNumberCB4682121

분자식C31H23BrO3

포뮬러 무게523.42

MOL 파일56073-10-0.mol

동의어(한글)

브로디파쿰

브로다이파쿰

2H-1-벤조피란-2-온, 3-[3-(4'-브로모[1,1'-바이페닐]-4-일)-1,2,3,4-테트라하이드로-1-나프탈렌일]-4-하이드록시-

화학적 성질

녹는점	228-230°
끓는 점	679.0±55.0 °C(Predicted)
밀도	1.2940 (rough estimate)
증기압	41 x l0^-6 Pa (20 °C)
굴절률	1.4620 (estimate)
저장 조건	0-6°C
용해도	클로로포름 (약간 용해됨), DMSO (약간 용해됨)
산도 계수 (pKa)	5.0 (weak acid, est.)
수용성	0.24mg l^-1(20°C)
Merck	13,1363
BRN	8171403
CAS 데이터베이스	56073-10-0(CAS DataBase Reference)
EPA	Brodifacoum (56073-10-0)

위험 및 안전 성명

위험품 표기	T+;N,N,T+
위험 카페고리 넘버	27/28-48/24/25-50/53
안전지침서	1/2-36/37-45-60-61
유엔번호(UN No.)	UN 2811
WGK 독일	3
RTECS 번호	GN4934750
위험 등급	6.1(a)
포장분류	I
유해 물질 데이터	56073-10-0(Hazardous Substances Data)
독성	LD50 orally in male, female field rats: 0.16, 0.18 mg/kg (Yuet-Ming)

그림문자(GHS)

브로디파쿰 MSDS

브로디파쿰 화학적 특성, 용도, 생산

개요
Brodifacoum is a 4-hydroxycoumarin anticoagulant that acts as a vitamin K antagonist. It was registered as a pesticide in 1979 in the United States although in 2008 it was made a restricted use pesticide by the Environmental Protection Agency. This means it can only be used by certified pesticide applicators; however, the makers of D-Con which contains 0.005% brodifacoum by weight have challenged this and brodifacoum is currently available in D-Con and in various other pesticide products for the eradication of mice and rats although it is also used on larger mammals such as possums. Brodifacoum currently remains available to the general public.
화학적 성질
White Solid
용도
Brodifacoum is a highly lethal vitamin K antagonist anticoagulant poison. In recent years, Broadifacoum, has become one of the world's most widely used pesticides.
위험도
Poison, anticoagulant.
환경귀착
Brodifacoum, like other hydroxycoumarins, interferes with the production of vitamin K–dependent coagulation factors. Vitamin K is a cofactor for the carboxylation of specific glutamic acid groups in coagulation factors II (prothrombin), VII, IX, and X. During this step, vitamin K is oxidized to vitamin K 2,3-epoxide. The regeneration of vitamin K by vitamin K 2,3-epoxide reductase is prevented by brodifacoum. As a result, dysfunctional decarboxy-coagulation factors are produced and coagulation is impaired. Brodifacoum is over 100 times more potent than warfarin on a molar basis in rats.
신진 대사 경로
The fate of brodifacoum in soils and plants has not been studied in detail because the compound is usually applied as a pelleted bait or in a wax block. This limits its dissipation in the environment. Studies in animals have been conducted as part of the assessment of safety and to investigate mode of action.

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