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그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Danger

• 유해·위험 문구

  H315：피부에 자극을 일으킴

  H319：눈에 심한 자극을 일으킴

  H334：흡입 시 알레르기성 반응, 천식 또는 호흡 곤란 등을 일으킬 수 있음

  H335：호흡 자극성을 일으킬 수 있음

• 예방조치문구

  P261：분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.

  P264：취급 후에는 손을 철저히 씻으시오.

  P264：취급 후에는 손을 철저히 씻으시오.

  P280：보호장갑/보호의/보안경/안면보호구를 착용하시오.

  P285：환기가 잘 되지 않는 곳에서는 호흡기 보호구를 착용하시오

  P302+P352：피부에 묻으면 다량의 물로 씻으시오.

  P304+P341：들이마신 경우,호흡이 어려운 경우 환자를 신선한 공기가 있는 곳으로 옮기고 호흡하기 편한 자세로 안정을 취하게 함

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

  P321：(…) 처치를 하시오.

  P332+P313：피부 자극이 생기면 의학적인 조치· 조언을 구하시오.

  P342+P311：호흡기 증상이 나타나면 의료기관(의사)의 진찰을 받으시오.

  P362：오염된 의복을 벗고 세척 후에 재사용하기

  P501：...에 내용물 / 용기를 폐기 하시오.

브로멜라인 MSDS

• Bromelain

브로멜라인 화학적 특성, 용도, 생산

• 화학적 성질

  White to light brownish yellow amorphous powder.
  Soluble in water,insoluble in ethanol, chloroform and ether.

• 용도

  Bromelain is used as a natural anti-inflammatory for conditions such as arthritis.

• 정의

  ChEBI: Bromelain is a milk-clotting proteolytic enzyme. It is precipitated from pineapple juice with acetone or ammonium sulfide. Protein-digesting and milk-clotting enzymes found in PINEAPPLE fruit juice and stem tissue. Enzymes from the two sources are distinguished as fruit bromelain and stem bromelain. This enzyme was formerly listed as EC 3.4.22.4.

• 용도

  Bromelain has been found to be used to tenderize meat, chill-proof beer, and produce protein hydrolysates.

• 제조 방법

  Bromelain is prepared from the juice of cooled pineapple through ultrafiltration, centrifugation, and lyophilization, which results in the production of a yellow powder. This process can succeed in a wide range of pH values.

• 일반 설명

  Bromelain is a crude extract from pineapple that contains a mixture of different proteases as well as phosphatases, glucosidases, peroxidases, cellulases, glycoproteins, and carbohydrates. Of the different proteases available in a bromelain mixture, commercial bromelain is usually produced from the stem part (stem bromelain), although other pineapple parts contain a certain amount of bromelain as well. Bromelain is an effective anticancer therapeutic agent, as a result of the systemic response to multiple cellular and molecular targets induced by this enzyme; however, the real underlying mechanisms are yet to be fully understood. Also, this enzyme has the potential to be used as an antibiotic since it can modify the permeability of organs and tissues to different drugs. Moreover, bromelain is used in a debridement cream formulation to eliminate burn debris and accelerate the healing process, and can inhibit platelet aggregation, especially for patients affected with heart attack and stroke, and reduce arthritis pathogenesis since it has analgesic properties that can influence pain mediators, and prevent diarrhea by interacting with intestinal secretory signaling pathways. In addition to food and medical applications, bromelain is used in the cosmetic industry to treat various skin conditions. It is also used as a stain remover in teeth cleaning/whitening. In the textile industry, it is used to improve the dyeing properties of protein fibers such as wool and silk and assist in the cocoon-softening process in silk production.
  

• 주요 응용

  Baking Industry: In the baking industry, bromelain is used for improving dough quality and rise. Gluten is a major component of wheat. As Gluten is insoluble in water, it forms a lattice-like structure. Bromelain removes gluten from wheat, ensuring proper dough formation. Bromelain is also used to produce flour of hypoallergic nature.
  Catering:Bromelain helps in the hydrolysis of myofibril proteins in meat, chicken, and oyster. The protease activity of the enzyme bromelain breaks collagen fiber leading to meat tenderization process. The sulfhydryl group of cysteine in the protease is responsible for the proteolytic action of collagen fiber, leading to the process of tenderization that makes the meat more palatable.
  Alcohol supply: Bromelain is used for enhancing the stability of the protein and preventing haziness in beer. Bromelain enhances the stability of the white-wine protein. The bromelain isolated from the stem was active at the minimum pH value of wine and showed an increase in the Ka value by 42%, acting as an alcoholic-acid buffer and thereby acting as an excellent protease enzyme in the production and stabilization of wine.
  Cosmetic: Bromelain can be used to treat acne and wrinkles, and to reduce swelling, bruising and drying of the skin. Bromelain proteolyses the protein of the upper layer of skin cells, paving a way for the replacement of young cells. The study also reports that the application of bromelain on the skin reduces the bruises caused during cosmetic surgeries.

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