パルミトイルトリペプチド-1

化学名:パルミトイルトリペプチド-1

CAS番号.147732-56-7

英語名:Palmitoyl Tripeptide-1

CBNumberCB81214020

MFC30H54N6O5

MW578.79

MOL File147732-56-7.mol

别名

パルミトイルトリペプチド-1

パルミトイルオリゴペプチド

パルミトイルトリペプチド-1物理性質

沸点	913.0±65.0 °C(Predicted)
比重(密度)	1.105
貯蔵温度	Store at -20°C
溶解性	DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 30 mg/ml
外見	A solid
酸解離定数(Pka)	3.16±0.10(Predicted)
シーケンス	Pal-Gly-His-Lys
InChIKey	BYUQATUKPXLFLZ-UIOOFZCWSA-N
SMILES	C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)CCCCCCCCCCCCCCC

危険有害性情報のコード(GHS)

パルミトイルトリペプチド-1 化学特性,用途語,生産方法

定義
本品は、アラニン(*)、アルギニン(*)、アスパラギン酸(*)、グリシン(*)、ヒスチジン(*)、リシン(*)、プロリン(*)、セリン(*)及びバリン(*)の中から選ばれた2種以上のアミノ酸からなる合成ペプチドのパルミチン酸アミド(*)である。参照表示名称：アラニン, アルギニン, アスパラギン酸, グリシン, ヒスチジン, リシン, プロリン, セリン, バリン, パルミチン酸アミド
化粧品の成分用途
皮膚コンディショニング剤、洗浄剤
説明
A peptide is two or more amino acids joined together and is the building block of protein. Peptides fall into three main categories: signal peptides, carrier peptides, and those that inhibit nerve signals. Signal peptides, like palmitoyl tripeptide-1, act as messengers to cells, which trigger collagen synthesis, which then increases skin firmness.Palmitoyl tripeptide-1 is a small three amino acid signal peptide with the amino sequence of glycine-histidine-lysine (GHK). GHK is attached to palmitic acid (a fatty acid) to increase its skin penetration and oil solubility.
使用
Palmitoyl Tripeptide-1, has shown to have effects on on collagen, fibronectin, hyaluronic acid synthesis in human dermal fibroblasts, and thus can be used in preparation of antiaging cosmetic creams.
主な応用
Palmitoyl Tripeptide-1 (Pal-GHK, SpecPed? PT1P) is useful in anti-aging products and wrinkle treatment products such as gels, serums, lotions and creams. Acting as messengers of cutaneous restructuration and repair, this peptide works synergistically to restore and maintain the skin's youthful appearance.
臨床応用
Applying palmitoyl tripeptide-1 directly to your skin tells the cells to make more collagen, stimulating new collagen production. It requires at least one month or more to begin to see visible changes from new collagen with maximum results visible after 3 to 4 months. Erin Gilbert, MD, FAAD, Ph.D., and board-certified dermatologist and neuroscientist, continues: "Peptides can be included in serums, moisturizers, and masks," Gilbert explains. "They are also included in some topical serums used after micro-needling or superficial laser procedures to increase the penetration of the peptide and help the skin recover from the procedure."
安全性
The CIR Expert Panel concluded that peptides, such as palmitoyl tripeptide-1, are safe in cosmetics and self-care products. Environmental Working Group (EWG) currently scores palmitoyl tripeptide-1 as “1” or “low hazard.”Overall, peptides, such as palmitoyl tripeptide-1, mimic what already exists in the human body and research on peptides’ impact on the skin shows limited to no skin irritation. In terms of toxicity caused by peptides, there is no published research to document any known toxicity.

パルミトイルトリペプチド-1 生産企業

147732-56-7, パルミトイルトリペプチド-1 キーワード

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