パルミトイルペンタペプチド-4

化学名:パルミトイルペンタペプチド-4

CAS番号.214047-00-4

英語名:Palmitoyl Pentapeptide

CBNumberCB51214034

MFC39H75N7O10

MW802.05

MOL File214047-00-4.mol

别名

パルミトイルペンタペプチド-4

パルミトイルペンタペプチド-4物理性質

沸点	1120.1±65.0 °C(Predicted)
比重(密度)	1.147
貯蔵温度	2-8°C(protect from light)
酸解離定数(Pka)	2.98±0.10(Predicted)
外見	Solid
色	White to off-white
シーケンス	pal-Lys-Thr-Thr-Lys-Ser-OH
InChIKey	WSGCRSMLXFHGRM-DEVHWETNSA-N
SMILES	C(O)(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCCCC

パルミトイルペンタペプチド-4 化学特性,用途語,生産方法

定義
本品は、パルミチン酸(*)とリシン(*)、セリン(*)及びトレオニン(*)残基からなる合成ペンタペプチドとの反応生成物である。参照表示名称：パルミチン酸, リシン, セリン, トレオニン
化粧品の成分用途
皮膚コンディショニング剤
説明
Palmitoyl pentapeptide-4 (formerly called palmitoyl pentapeptide-3) was the fi rst big successful breakthrough peptide ingredient and probably the most commonly used peptide for aging skin. Also known as Matrixyl?, palmitoyl pentatpeptide-4 has been demonstrated to signifi cantly increase collagen synthesis, improving the appearance of wrinkles and sagging of the aging skin. Palmitoyl pentapeptide-4 is basically a sequential piece of a collagen molecule. It is theorized to work by “tricking” the skin into “believing” that too much collagen has been broken down, thereby curbing the production of collagenase, the enzyme that destroys collagen, and stimulating fi broblasts, the cells that produce collagen. The results of using palmitoyl pentapeptide-4 are remarkable, and the performance ingredient does not cause the irritation that can be caused by other antiaging ingredients such as retinol.
使用
palmitoyl pentapeptide-4 is a skin conditioner. Clinical studies by manufacturers credit it with an ability to promote collagen, elastin, and glycosaminoglycan synthesis. This would result in an ability to restore skin thickness, which diminishes with age, and to reduce the appearance of lines and wrinkles. Palmitoyl pentapeptide4 is a synthetic peptide with serine, threonine, and hexa decanoyl derivatives.
palmitoyl tetrapeptide-7 is formerly known as palmitoyl tetrapeptide3. This peptide appears to improve skin elasticity and firmness. It also hydrates, smoothes, and protects the skin. It can be both obtained from the plant and synthetically derived and is found in a variety of different skin care preparations including eye lotions, moisturizers, and night creams. Palmitoyl tetrapeptide3 appears to act as an anti-inflammatory. This is attributed to its ability to control the secretion of specific chemicals responsible for skin aging (i.e., cytokines and interleukin-6), and hence it may function in a manner similar to the anti-aging hormone, DHeA. Some studies indicate that palmitoyl tetrapeptide-7 may also act as a uV filter.
作用機序
Palmitoyl Pentapeptide appears to work by increasing collagen production, stimulating collagen, elastin, and hyaluronic acid growth, increasing the skin's moisture content and retention, which helps reduce the appearance of fine lines and wrinkles on the skin's surface. Pentapeptide is equivalent to intimate integration with the skin, changing the skin ecology and cell repair, and playing the role of intracellular hormones and enzymes.

パルミトイルペンタペプチド-4 上流と下流の製品情報

パルミトイルペンタペプチド-4 生産企業

214047-00-4, パルミトイルペンタペプチド-4 キーワード

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