2-[エトキシ(イソプロピルアミノ)チオホスフィニルオキシ]安息香酸イソプロピル

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H225：引火性の高い液体および蒸気

  H319：強い眼刺激

  H412：長期的影響により水生生物に有害

• 注意書き

  P210：熱/火花/裸火/高温のもののような着火源から遠ざ けること。－禁煙。

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

2-[エトキシ(イソプロピルアミノ)チオホスフィニルオキシ]安息香酸イソプロピル 価格

2-[エトキシ(イソプロピルアミノ)チオホスフィニルオキシ]安息香酸イソプロピル 化学特性,用途語,生産方法

• 外観

  無色澄明の液体

• 溶解性

  イソプロパノール, ヘキサン, ジクロロメタン, トルエン>200g/l(20℃)。水:18mg/l(20℃)アセトンに溶け、水にほとんど溶けない。

• 用途

  イソフェンホス試験用標準品。

• 農薬用途

  殺虫剤

• 使用上の注意

  アルゴン封入

• 化学的特性

  Isofenphos is a colorless oil at room temperature. It is sparingly soluble in water, but soluble in cyclohexone, toluene, acetone, and diethyl ether. The US EPA has grouped isofenphos under RUP, which indicates that qualifi ed, certifi ed, and trained workers are required in the safety management of isofenphos. It is used on turf and ornamental trees and shrubs to control white grubs, mole crickets, and other insects, such as soil-dwelling insects, cabbage root fl ies, corn roundworms, and wire worms.

• 使用

  Isofenphos is an organophosphorus insecticide used in soil to control leaf-eating and soil-dwelling pests in vegetables, fruits, turf and field crops.

• 一般的な説明

  Colorless oil. Non corrosive. Used as an insecticide.

• 空気と水の反応

  Hydrolyzed by alkali solution.

• 反応プロフィール

  Organothiophosphates, such as ISOFENPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

• 健康ハザード

  Exposures to isofenphos are highly toxic to animals and humans. Acute and prolonged exposures to high concentrations of isofenphos has caused poisoning with symptoms such as increased secretions, diffi culty in breathing, diarrhea, urination, pupil contraction, slowness of the heart, convulsions, and coma. Isofenphos in combination with malathion cause severe poisoning in humans.

• 環境運命予測

  Soil. Rapidly degraded by microbes via oxidative desulfuration in soils forming isofenphos oxon (Abou-Assaf et al., 1986; Abou-Assaf and Coats, 1987; Somasundarum et al., 1989), isopropyl salicylate and carbon dioxide (Somasundaram et al., 1989). The formation of isofenphos oxon is largely dependent upon the pH, moisture and temperature of the soil. The degradation rate of isofenphos decreased with a decrease in temperature (35°C >25°C >15°C), moisture content (22.5% >30% >15%) and in acidic and alkaline soils (pH 6 and 8 >pH 7). After isofenphos was applied to soil at a rate of 1,12 kg/ai/ha, concentrations of 8.3, 7.2, 5.1 and 1.0 ppm were found after 5, 21, 43 and 69 days, respectively. Following a second application, 4.9, 1.55, 0.25 and 0.10 ppm of isofenphos were found after 5, 21, 43 and 69 days, respectively (Abou-Assaf and Coats, 1987).
  A pure culture of Arthrobacter sp. was capable of degrading isofenphos at different soil concentrations (10, 50 and 100 ppm) in less than 6 hours. In previously treated soils,isofenphos could be mineralized to carbon dioxide by indigenous microorganisms (
  Plant. Two weeks following application to thatch, 65% of the applied amount was present (Sears et al., 1987).
  Surface Water. In estuarine water, the half-life of isofenphos ranged from 9.8 to 11.9 days (Lacorte et al., 1995).
  Photolytic. Irradiation of an isofenphos (500 mg) in hexane and methanol (100 mL) using a high pressure mercury lamp (l = 254–360 nm) for 24 hours yielded the following products: isofenphos oxon and O-ethyl hydrogen-N-isopropylphosphoroamidothioa

• 代謝経路

  14C-Isofenphos is bioactivated by mixed-function oxidases that ultimately give N-desisopropylisofenphos oxon, a product with 2300-fold greater inhibitory potency than isofenphos oxon towards housefly head acetylcholinesterase.271 By housefly and the cuperous chafer, isofenphos is metabolized to give detoxified metabolites without the bioactivated N- desisopropylisofenphos oxon. No difference in kinds of metabolite is found between the two insects. When rats are administered 14C-isofenphos, most of the radioactivity is recovered from the water fraction of the urine and feces. Aminoisofenphos and isofenphos oxon are detected in the benzene fraction, and the other six metabolites are identified as water-soluble metabolites which include O-ethylhydrogen phosphoramidate and O-ethylhydrogen isopropylphosphoramidothioate. Water-soluble metabolites are predominantly formed through cleavage of the P-O-aryl linkage.

• 代謝

  Main degradation route is cleavage of the P?O-aryl ester linkage through oxidative desulfuration to isofenphos oxon followed by hydrolysis and oxidative dearylation from isofenphos. In plant, the major metabolites are salicylic acid and dihydroxybenzoic acid.

2-[エトキシ(イソプロピルアミノ)チオホスフィニルオキシ]安息香酸イソプロピル 上流と下流の製品情報

2-[エトキシ(イソプロピルアミノ)チオホスフィニルオキシ]安息香酸イソプロピル スペクトルデータ(¹HNMR、¹³CNMR、IR1、MS)

25311-71-1, 2-[エトキシ(イソプロピルアミノ)チオホスフィニルオキシ]安息香酸イソプロピル キーワード