イソプロピルアミン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H224：極めて引火性の高い液体および蒸気

  H314：重篤な皮膚の薬傷?眼の損傷

  H335：呼吸器への刺激のおそれ

• 注意書き

  P210：熱/火花/裸火/高温のもののような着火源から遠ざ けること。－禁煙。

  P233：容器を密閉しておくこと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P303+P361+P353：皮膚（または髪）に付着した場合：直ちに汚染された衣 類をすべて脱ぐこと/取り除くこと。皮膚を流水/シャワー で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P403+P233：換気の良い場所で保管すること。容器を密閉 しておくこと。

イソプロピルアミン 価格

イソプロピルアミン 化学特性,用途語,生産方法

• 外観

  無色～ほとんど無色, 澄明の液体

• 溶解性

  水, アルコール, エーテルに易溶。水、エタノール及びアセトンに極めて溶けやすい。

• 解説

  2-アミノプロパンともいわれ，n -プロピルアミンの異性体である。化学式 (CH3)2CHNH2 。イソプロピルアミンは，アンモニア臭をもつ無色可燃性の液体で，沸点 34℃。強塩基性を示し，水，アルコール，エーテルによく溶ける。

  ブリタニカ国際大百科事典 小項目事典 ブリタニカ
  

• 用途

  有機合成(和光試薬時報Vol.62 No.3,p.29(1994))。

• 用途

  乳化剤、界面活性剤、医薬農薬原料

• 用途

  医薬?染料中間体,、農薬?界面活性剤原料

• 説明

  Isopropylamine (propan-2-amine, IUPAC) is a colorless, volatile liquid. It is highly flammable, with a flammable range of 2%–10.4% in air. Boiling point is 93°F (33°C), flash point is ?15°F (?26°C), and ignition temperature is 756°F (402°C).
  It is miscible with water, with a specific gravity of 0.69, which is lighter than water. Vapor density is 2.04, which is heavier than air. In addition to flammability, isopropylamine is a strong irritant to tissue and has a TLV of 5 ppm in air. The four-digit UN identification number is 1221. The NFPA 704 designation for isopropylamine is health 3, flammability 4, and reactivity 0. Primary uses for isopropylamine are pharmaceuticals, dyes, insecticides, and as a dehairing agent.

• 化学的特性

  Isopropylamine is a colorless, flammable liquid. Isopropylamine is miscible with water, alcohol, and ether.The odor threshold reportedly ranges from 0.21 to 0.70 ppm; the pungent, ammoniacal odor becomes irritating at 24mg/m3 (110).

• 物理的性質

  Colorless liquid with a penetrating, ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 500 μg/m³ (210 ppb_v) and 1.7 mg/m³ (700 ppb_v), respectively (Hellman and Small, 1974). An odor threshold concentration of 25 ppb_v was reported by Nagata and Takeuchi (1990).

• 天然物の起源

  Not reported found in natu

• 使用

  Isopropylamine is used as a dehairing agentand as an intermediate in the preparation ofmany organics.

• 調製方法

  Isopropylamine can be produced from the corresponding alcohol by reacting with ammonia in the presence of a dehydrating catalyst, or from the chloride by reacting with ammonia under pressure. It is also reported that this amine can be produced from acetone and ammonia or from the acetone oxime (HSDB 1989).

• 定義

  ChEBI: A member of the class of alkylamines that is propane carrying an amino group at position 2.

• 一般的な説明

  A clear colorless liquid with an ammonia-like odor. Flash point -35°F. Boiling point 90°F. Less dense than water Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a solvent and to make other chemicals.

• 空気と水の反応

  Highly flammable. Water soluble.

• 反応プロフィール

  Isopropylamine is a colorless, alkaline liquid, very volatile, moderately toxic, highly flammable. Dangerous fire hazard when exposed to heat, flame, sparks, or strong oxidizers. When heated to decomposition Isopropylamine emits toxic fumes of oxides of nitrogen [M. K.]. A mixture of Isopropylamine and perchloryl fluoride resulted in an uncontrolled oxidation and/or explosion, [J. Org. Chem., 1980, 45, 4036]. The reaction of 1-chloro-2,3-epoxypropane and the amine and most probably other nitrogen bases, yields a violent exotherm, [Chem. & Ind., 1971, 994].

• 危険性

  Highly flammable, dangerous fire risk. Strong irritant to tissue.

• 健康ハザード

  Isopropylamine is a strong irritant to theeyes, skin, and respiratory system. A shortexposure to 10–20 ppm can cause irritationof the nose and throat in humans (Procturand Hughes 1978). Prolonged exposure tohigh concentrations may lead to pulmonaryedema. Skin contact can cause dermatitisand skin burns. Exposure to 8000 ppm for4 hours was lethal to rats.
  LD50 value, oral (mice): 2200 mg/kg.

• 化学反応性

  Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

• 工業用途

  Isopropylamine can be used as a dehairing agent and as a solvent. It also finds use as an intermediate in the production of insecticides, herbicides and bactericides and in the production of pharmaceuticals, dyes and rubber accelerators (HSDB 1989).

• 環境運命予測

  Photolytic. Low et al. (1991) reported that the photooxidation of aqueous primary amine solutions by UV light in the presence of titanium dioxide resulted in the formation of ammonium and nitrate ions.
  Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987). Forms water-soluble salts with acids.

• 代謝

  One would expect isopropylamine to be readily absorbed from the gut and respiratory tract. Shorter chain aliphatic amines such as isopropylamine also are efficiently absorbed through the skin (Beard and Noe 1981). When administered intravenously, isopropylamine distributed rapidly into tissue compartments with tissue/plasma ratios ranging from 1.8 in the atrium to 16.7 in the renal medulla (Privitera et al 1982). During the elimination phase, a half-life of 146 min was observed in plasma. There do not appear to be any definitive metabolic studies with this compound, however through a comparison with other substrates, one might expect oxidation to acetone and ammonia through the action of monoamine oxidase (Tipton 1980).

イソプロピルアミン 上流と下流の製品情報

イソプロピルアミン 生産企業

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イソプロピルアミン スペクトルデータ(¹HNMR、¹³CNMR、IR1、IR2、MS、Raman)

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