2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール

化学名:2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール

CAS番号.20675-51-8

英語名:cannabichromene

CBNumberCB61400957

MFC21H30O2

MW314.46

MOL File20675-51-8.mol

别名

カンナビクローム

2-メチル-7-ペンチル-2-(4-メチル-3-ペンテニル)-2H-1-ベンゾピラン-5-オール

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール物理性質

融点	145°C
沸点	394.13°C (rough estimate)
比重(密度)	1.0536 (rough estimate)
屈折率	1.5404 (estimate)
闪点	9℃
貯蔵温度	-20°C
溶解性	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
外見	Oil
酸解離定数(Pka)	9.68±0.40(Predicted)
色	クリスタル
InChI	InChI=1S/C21H30O2/c1-5-6-7-10-17-14-19(22)18-11-13-21(4,23-20(18)15-17)12-8-9-16(2)3/h9,11,13-15,22H,5-8,10,12H2,1-4H3
InChIKey	UVOLYTDXHDXWJU-UHFFFAOYSA-N
SMILES	C1(C)(CC/C=C(\C)/C)OC2=CC(CCCCC)=CC(O)=C2C=C1
LogP	8.560 (est)

安全性情報

RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
HSコード	9999999999
毒性	dni-hmn:lyms 100 mmol/L FEPRA7 36,1748,77

危険有害性情報のコード(GHS)

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール価格

製品番号	包装	価格	製品説明	購入
Sigma-Aldrich Japan C-143	1ml	￥35700	1.0?mg/mL in methanol, ampule of 1?mL, certified reference material	購入

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール化学特性,用途語,生産方法

説明
Cannabichromene (CBC) is one of the most abundant cannabinoids found in the cannabis plant, next to CBD, THC, and CBG. It is particularly abundant in freshly harvested dry-type Cannabis material, and it is the second most abundant cannabinoid in some strains of marijuana growing in the USA. Like CBD, CBG does a poor job of binding to the endocannabinoid system's CB1 and CB2 receptors and is a non-psychoactive compound. Instead, CBC has been observed to have unique interactions with TRPV1 and TRPA1 receptors (vanilloid 1 and ankyrin 1 receptors). It has modest antinociceptive and anti‐inflammatory effects and potentiates some effects of Δ9‐tetrahydrocannabinol in vivo[1–2].
生物学の機能
More recently, it has been shown that cannabichromene (CBC) exerts antimicrobial, anti-inflammatory, analgesic and antidepressant-like activity in rodents. Pharmacodynamic studies have shown that CBC, like other plant natural products, is an inhibitor of endocannabinoid cellular reuptake and a weak inhibitor of monoacylglycerol lipase (MAGL) but is also a potent activator of transient receptor potential (TRP) ankyrin 1-type (TRPA1) channels. CBC was also recently found to stimulate the descending pathway of antinociception in the ventrolateral periaqueductal grey, probably through activation of TRPA1, inhibition of endocannabinoid inactivation and subsequent elevation of local endocannabinoid levels, and possibly via potentiation of adenosine signalling[3].
一般的な説明
Cannabichromene (CBC) is a non-psychoactive cannabinoid of Cannabis that reportedly exerts anti-inflammatory, antimicrobial and analgesic activity. This Certified Snap-N-Spike^? solution standard is suitable for cannabichromene testing methods by GC/MS, HPLC or LC-MS/MS for Cannabis potency testing or impurity profiling, pharmaceutical research, and forensic analysis. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.
副作用
Dry Mouth: Similar to other cannabinoids, CBC can cause dry mouth. Staying hydrated can help mitigate this effect.
Fatigue: Some users feel tired after taking it, especially in higher doses. It's advisable to start with a low dose and gradually increase it to find the optimal amount.
Digestive Issues: In rare cases, it might cause mild digestive issues such as nausea or diarrhoea. Headache: Some people might experience headaches, particularly when starting or taking higher doses.
Dizziness: Occasional dizziness can occur, especially when standing up too quickly after consuming CBC.
安全性プロファイル
Poison by intravenous and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. Whenheated to decomposition it emits acrid smoke and irritating fumes

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール生産企業

20675-51-8, 2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オールキーワード

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2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール

危険有害性情報のコード(GHS)

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール 価格

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール 化学特性,用途語,生産方法

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール 生産企業

20675-51-8, 2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール キーワード

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール価格

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール化学特性,用途語,生産方法

2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オール生産企業

20675-51-8, 2-メチル-2-(4-メチル-3-ペンテニル)-7-ペンチル-2H-1-ベンゾピラン-5-オールキーワード