(2E,6E,10E)-2,6,9,9-テトラメチル-2,6,10-シクロウンデカトリエン-1-オン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H317：アレルギー性皮膚反応を起こすおそれ

  H400：水生生物に強い毒性

• 注意書き

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

(2E,6E,10E)-2,6,9,9-テトラメチル-2,6,10-シクロウンデカトリエン-1-オン 価格

(2E,6E,10E)-2,6,9,9-テトラメチル-2,6,10-シクロウンデカトリエン-1-オン 化学特性,用途語,生産方法

• 使用

  Zerumbone has been used:
  
  • for liquid chromatography with mass spectrometry (LC-MS-MS)
  • to investigate its potential application in the prevention
  • treatment of esophageal squamous cell carcinomas (ESCC)
  
  

• 定義

  ChEBI: A sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds. It is obtained by steam distillati n from a type of edible ginger, Zingiber zerumbet Smith, grown particularly in southeast Asia.

• 一般的な説明

  This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

• 抗がん研究

  Zerumbone is isolated from the rhizomes of the wild ginger Zingiber zerumbet. It isfound to suppress the proliferation of breast cancer and colon cancer cells and alsoto prevent initiation and promotion of skin cancer in mice. It also suppresses theNF-κB activation and its sequential suppression of IκBα kinase activity, IκBαphosphorylation, IκBα degradation, p65 phosphorylation, nuclear translocation,and acylation. It downregulates the NF-κB-regulated gene products like FLIP, cyclinD1, TRAF1, COX2, Bfl-1/A1, MMP-9, Bcl-xL, ICAM-1, Bcl-2, c-myc, XIAP,survivin, IAP1, and IAP2, and thus, it potentiates apoptosis (Murakami et al. 2002;Sakinah et al. 2007).

(2E,6E,10E)-2,6,9,9-テトラメチル-2,6,10-シクロウンデカトリエン-1-オン 生産企業

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(2E,6E,10E)-2,6,9,9-テトラメチル-2,6,10-シクロウンデカトリエン-1-オン スペクトルデータ(¹HNMR)

471-05-6, (2E,6E,10E)-2,6,9,9-テトラメチル-2,6,10-シクロウンデカトリエン-1-オン キーワード