アロセトロン塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H301：飲み込むと有毒

  H319：強い眼刺激

  H412：長期的影響により水生生物に有害

• 注意書き

  P273：環境への放出を避けること。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

アロセトロン塩酸塩 価格

アロセトロン塩酸塩 化学特性,用途語,生産方法

• 外観

  白色～うすい黄色粉末～結晶

• 効能

  制吐薬, セロトニン5-HT3受容体拮抗薬

• 説明

  Lotronex (alosetron) was developed for the treatment of severe irritable bowel syndrome (IBS), and was approved for use by the US Food and Drug Administration (FDA) in 2000. Although Lotronex had a relatively high improvement rate in patients taking the drug for IBS, it was voluntarily pulled from the market by GlaxoWellcome that same year due to reports of severe adverse side effects, some resulting in death.
  In 2002, Lotronex was reapproved in a supplemental New Drug Application for use under more restrictive conditions. Now with a risk management program to be consulted prior to administration of the drug, Lotronex is designated to be prescribed only when its medical benefits outweigh the risks of toxic effects; women with severe diarrhea-predominant IBS are now the focal point of prescriptions for Lotronex.

• 化学的特性

  Alosetron hydrochloride is Crystalline Solid

• 使用

  Alosetron hydrochloride is used in treatment of irritable bowel syndrome

• 定義

  ChEBI: The hydrochloride salt of alosetron.

• 環境運命予測

  The environmental fate and behavior of Lotronex is uncertain, as formal studies regarding its release into the environment are virtually nonexistent in the literature. Limited water solubility (61 mg ml^-1) may lead to persistence in soils, and in sediment following aquatic release, although specific fates with regard to degradation, bioaccumulation, and transport are unknown.

アロセトロン塩酸塩 上流と下流の製品情報

アロセトロン塩酸塩 生産企業

Global(249)Suppliers

アロセトロン塩酸塩 スペクトルデータ(¹HNMR)

122852-69-1, アロセトロン塩酸塩 キーワード