ピペブゾン

ピペブゾン 化学特性,用途語,生産方法

• Originator

  Elarzone, Dausse, France ,1973

• Manufacturing Process

  77 g (0.25 mol) of phenylbutazone, 30 ml of a 30% strength solution of formaldehyde and 50 ml of ethyl alcohol are introduced into a 500 ml flask, 25 g (0.25 mol) of N-methylpiperazine are slowly added to this mixture which is stirred mechanically. The mixture is then heated for one hour on a water bath, left to cool, and crystallization started by scratching.
  After being left in the refrigerator overnight the mixture, which has set solid, is triturated with 50 ml of isopropyl alcohol and the solid product filtered off and dried in vacuo over phosphorus pentoxide. 63 g (60% yield) of 1,2diphenyl-3,5-dioxo-4-n-butyl-4-(N'-methylpiperazinomethyl)pyrazolidine are obtained, melting at 129°C after recrystallization from 150 ml of isopropyl alcohol.

• Therapeutic Function

  Antiinflammatory

ピペブゾン 上流と下流の製品情報

ピペブゾン 生産企業

Global(4)Suppliers

27315-91-9, ピペブゾン キーワード