シクラシリン

シクラシリン 化学特性,用途語,生産方法

• 効能

  抗生物質, 細胞壁合成阻害薬

• 説明

  Ciclacillin was synthesized by Wyeth Laboratories in 1967 in the course of studies on the improvement of oral absorption of ampicillin. Although its antibacterial activity is one-sixteenth to one-half that of ampicillin, it shows a four to tenfold higher oral absorption and higher urinary excretion. Ciclacillin shows less tendency than ampicillin to cause diarrhea and is used for therapy of pyoderma, wound infection, respiratory and urinary tract infections, as well as ear and nose, and other infections caused by Staphylococcus, Streptococcus, Escherichia coli, Citrobacter, Klebsiella, Proteus, and Haemophilus influenzae.

• 使用

  Antibacterial.

• 抗菌性

  The structure differs from other aminopenicillins in that the benzene ring is completely saturated and the amino substituent is attached directly to it instead of being linked to an adjacent carbon atom. It is less active than ampicillin against staphylococci, streptococci and H. influenzae, but is better absorbed by mouth, peak plasma levels of 10–18 mg/L being reached after a 500 mg oral dose. Its pharmacokinetic properties, side effects and use resemble those of ampicillin. It has limited availability.

シクラシリン 上流と下流の製品情報

シクラシリン 生産企業

Global(16)Suppliers

3485-14-1, シクラシリン キーワード