イプロニアジド
化学名:イプロニアジド
CAS番号.54-92-2
英語名:iproniazid
CBNumberCB0928533
MFC9H13N3O
MW179.22
MOL File54-92-2.mol
别名
イプロニアジド
1-イソニコチノイル-2-イソプロピルヒドラジン
イソニコチン酸2-イソプロピルヒドラジド
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イプロニアジド物理性質
| 融点 | 112.5-113.5° |
| 沸点 | 311.75°C (rough estimate) |
| 比重(密度) | 1.1305 (rough estimate) |
| 屈折率 | 1.5100 (estimate) |
| 貯蔵温度 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 溶解性 | DMSO（微量）、メタノール（微量） |
| 酸解離定数(Pka) | 11.28±0.23(Predicted) |
| 外見 | 個体 |
| 色 | ペールベージュ |
| CAS データベース | 54-92-2 |
| HSコード | 2933399990 |
| 毒性 | An isopropyl derivative of isoniazid that was found to have mood-elevating effects in tuberculosis patients. It was later found to be a monoamine oxidase (MAO) inhibitor and, although not currently approved for clinical use as an antidepressant due to its propensity to cause liver damage it led to the development of other MAO inhibitors currently in use. In addition to hepatotoxic effects, iproniazid is a hypotensive agent and can cause potentially hazardous reactions with other drugs and amine-rich foods. |
