硝酸ミコナゾール

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H317：アレルギー性皮膚反応を起こすおそれ

• 注意書き

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

硝酸ミコナゾール 価格

硝酸ミコナゾール 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色, 結晶性粉末～粉末

• 溶解性

  N,N-ジメチルホルムアミドに溶けやすく、メタノールにやや溶けにくく、エタノール、アセトン、又は酢酸に溶けにくく、水又はジエチルエーテルに極めて溶けにくい。エタノール及びアセトンに溶けにくく、水に極めて溶けにくい。

• 用途

  薬理研究用

• 用途

  イミダゾール系抗菌剤です。 広い抗菌スペクトルを示し、各種真菌に対し て強い抗菌作用を示します。

• 効能

  抗真菌薬, エルゴステロール合成阻害薬

• 商品名

  フロリード (持田製薬); フロリード (持田製薬)

• 説明

  Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candida spp.

• 化学的特性

  White Solid

• 使用

  Antifungal (topical).

• 一般的な説明

  Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Miconazole nitrate is an imidazole derivative and a broad spectrum antifungal drug used in the management of fungal outbreak in humans and veterinary animals.

• 生物活性

  Antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species.

• 臨床応用

  1-[2-(2,4-Dichlorophenyl)-2-[2,4-dichlorophenyl]-methoxy]ethyl]-1H-imidazole mononitrate (Monistat,Micatin) is a weak base with a pKa of 6.65. The nitric acidsalt occurs as white crystals that are sparingly soluble inwater and most organic solvents.
  The free base is available in an injectable form, solubilized with polyethylene glycol and castor oil, and intended for the treatment of serious systemic fungal infections, such as candidiasis, coccidioidomycosis, cryptococcosis, petriellidiosis, and paracoccidioidomycosis. It may also be used for the treatment of chronic mucocutaneous candidiasis. Although serious toxic effects from the systemic administration of miconazole are comparatively rare, thrombophlebitis, pruritus, fever, and gastrointestinal upset are relatively common. Miconazole nitrate is supplied in various dosage forms (cream, lotion, powder, and spray) for the treatment of tinea infections and cutaneous candidiasis. Vaginal creams and suppositories are also available for the treatment of vaginal candidiasis. A concentration of 2% of the salt is used in most topical preparations.

硝酸ミコナゾール 上流と下流の製品情報

硝酸ミコナゾール 生産企業

Global(722)Suppliers

硝酸ミコナゾール スペクトルデータ(¹HNMR、IR1、IR2、MS)

22832-87-7, 硝酸ミコナゾール キーワード