Description
4-Iodo-3-hydroxypyridine is an organic intermediate, commonly used in the synthesis of various pharmaceutical and chemical products. It is reported in the literature that 4-iodo-3-hydroxypyridine can be prepared from 2-chloro-4-iodopyridine in one step or from 3-hydroxypyridine in three steps.
Application
4-Iodo-3-hydroxypyridine is an organic intermediate and pharmaceutical intermediate, which is commonly used in the synthesis of various pharmaceutical and chemical products and in laboratory research and development processes.
Synthesis
4-Iodo-3-hydroxypyridine can be prepared by reacting 3-hydroxypyridine, potassium tert-butoxide, and methoxymethyl chloride in a nitrogen atmosphere.
References
[1] Patent: US2010/93720, 2010, A1. Location in patent: Page/Page column 57
[2] Journal of Organic Chemistry, 2005, vol. 70, # 2, p. 489 - 498
