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alpha-Amyrin

alpha-Amyrin Structure
alpha-Amyrin
  • CAS No.638-95-9
  • Chemical Name:alpha-Amyrin
  • CBNumber:CB9767508
  • Molecular Formula:C30H50O
  • Formula Weight:426.73
  • MOL File:638-95-9.mol
alpha-Amyrin Property
  • Melting point 178-183°C
  • alpha D17 +91.6° (c = 1.3 in benzene)
  • Boiling point bp0.7 243°
  • Density 0.9600 (rough estimate)
  • refractive index 1.4910 (estimate)
  • solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
  • pka 15.18±0.70(Predicted)
  • form Solid
  • color White to off-white
  • optical activity +93.3 (c 5.55, C6H6)
  • BRN 1916550
  • LogP 10.636 (est)
  • CAS DataBase Reference 638-95-9(CAS DataBase Reference)
  • FDA UNII 30ZAG40J8N
  • NIST Chemistry Reference «ALPHA»-amyrin(638-95-9)
  • EPA Substance Registry System Urs-12-en-3-ol, (3.beta.)- (638-95-9)
  • UNSPSC Code 85151701
  • NACRES NA.24
Safety
  • Hazard Codes  :Xi
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P264-P270-P301+P312-P501
alpha-Amyrin Price More Price(2)
  • Brand: Sigma-Aldrich
  • Product number: 53017
  • Product name : α-Amyrin
  • Purity: analytical standard
  • Packaging: 10MG
  • Price: ₹28513.05
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 53017
  • Product name : α-Amyrin
  • Purity: analytical standard
  • Packaging: 10MG
  • Price: ₹28513.05
  • Updated: 2022/06/14
  • Buy: Buy

alpha-Amyrin Chemical Properties,Usage,Production

  • Uses a-Amyrin is a natural chemical compound of the triterpene class. It is a pentacyclic triterpenol widely distributed in nature and has been isolated from a variety of plant sources such as epicuticular wax.
  • Definition ChEBI: A pentacyclic triterpenoid that is ursane which contains a double bond between positions 12 and 13 and in which the hydrogen at the 3beta position is substituted by a hydroxy group.
  • Biological Activity Triterpene th at has broad-spectrum analgesic properties for which the underlying mechanism is poorly understood but which may involve the inhibition of protein kinase A (PKA).
  • in vivo

    α-Amyrin (50, 100, 200 mg/kg orally, once daily for 42 days) can reduce the survival rate of rats with metabolic syndrome induced by high fructose diet[2].
    α-Amyrin (2 or 4 mg/kg, orally) improves cognitive dysfunction caused by low cholinergic neurotransmission in mice by activating ERK and GSK-3β signaling pathways[3].

    Animal Model:High-fructose diet (HFD)-induced metabolic syndrome in rats[2]
    Dosage:50, 100, 200 mg/kg
    Administration:p.o.
    Result:Decreased systolic blood pressure, plasma glucose, total cholesterol, and plasma triglycerides.
    Attenuated hepatic oxidative stress as well as micro- and macrovesicular fatty changes in hepatocytes caused by HFD.
    Animal Model:Scopolamine-Induced Memory Impairment Mice[3]
    Dosage:2 or 4 mg/kg
    Administration:p.o.
    Result:Increased the expression levels of phosphorylated extracellular signal-regulated kinase 1/2 (pERK) and phosphorylated glycogen synthase kinase-3β (pGSK-3β).
  • Purification Methods Purify it by acetylation to the acetate followed by hydrolysis and recrystallisation from aqueous MeOH or from EtOH. The acetate when crystallised from pet ether, n-heptane or CHC
alpha-Amyrin Preparation Products And Raw materials
Raw materials
Preparation Products
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alpha-Amyrin Spectrum
638-95-9, alpha-AmyrinRelated Search:
  • Building block
  • Tri-Terpenoids
  • 萜类
  • 抑制剂
  • 试剂
  • 标准品，对照品
  • 标准品
  • 植物提取物
  • AM to AQ
  • Analytical Standards
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • 伪-AMYRIN
  • (3S,4AR,6AR,6BS,8AR,11R,12S,12AR,14AR,14BR)-4,4,6A,6B,8A,11,12,14B-八甲基-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,14,14A,14B-二十氢苉-3-醇
  • Α-香树脂醇 标准品
  • Α-香树脂醇,ALPHA-香树精
  • ALPHA-香树精(ALPHA-香树脂醇)
  • Α-香树脂醇
  • Α-香树脂素
  • Α-香树精
  • Α-香树脂
  • Α-香树脂素A
  • ALPHA-香树脂醇
  • A-香树脂醇
  • alpha-香树精
  • 638-95-9
  • urs-12-en-3β-ol
  • AmyrinA-(AS)
  • α-Amyrin-RM
  • (3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol
  • α-Amyrine
  • e-Amyrin
  • α-Amyrin
  • Urs-12-en-3-ol, (3β)-
  • 4,4,6a,6b,8a,11,12,14b-octamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-ol
  • Urs-12-en-3-ol, (3beta)-
  • Urs-12-en-3-ol
  • alpha-Amyrine
  • alpha-Amyrenol
  • alfa-Amyrin
  • DELTA-AMYRIN
  • VIMINALOL
  • URS-12-EN-3-BETA-OL
  • 12-URSEN-3-BETA-OL
  • (3BETA)-URS-12-EN-3-OL
  • ALPHA-AMYRIN
  • AMYRIN, A-
  • A-AMYRIN
  • alpha-AMYRIN hplc
  • A-AMYRIN WITH HPLC
  • α-Amyrin,Urs-12-en-3β-ol, Viminalol
  • Urs-12-en-3-ol, (3b)-
  • 3b-Hydroxyurs-12-ene
  • (3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-Octamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-ol
  • Urs-12-en-3β-ol, Viminalol

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