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UVAOL

UVAOL Structure
UVAOL
  • CAS No.545-46-0
  • Chemical Name:UVAOL
  • CBNumber:CB1200999
  • Molecular Formula:C30H50O2
  • Formula Weight:442.72
  • MOL File:545-46-0.mol
UVAOL Property
  • Melting point 223-225 °C (lit.)
  • Boiling point 523.7±50.0 °C(Predicted)
  • Density 1.05±0.1 g/cm3(Predicted)
  • storage temp. -20°C Freezer
  • solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
  • form Solid
  • pka 15.09±0.10(Predicted)
  • color White to Off-White
  • LogP 9.130 (est)
  • CAS DataBase Reference 545-46-0
  • FDA UNII W599R31ROT
  • UNSPSC Code 12352103
  • NACRES NA.25
Safety
  • Risk Statements  :22
  • Safety Statements  :22-45
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
UVAOL Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: U6628
  • Product name : Uvaol
  • Purity: ≥95%
  • Packaging: 25MG
  • Price: ₹8172.88
  • Updated: 2022/06/14
  • Buy: Buy

UVAOL Chemical Properties,Usage,Production

  • Uses Uvaol can attenuate pleuritis and eosinophillic inflammation in mice that is induced by ovalbumin. It is an essential reagent in the synthesis of aminopropoxytriterpenoids that have anticancer activity.
  • Definition ChEBI: A natural product found in Rhododendron ferrugineum.
  • Biological Activity Uvaolexerts pharmacological properties such as antioxidant, anticancer, anti-inflammatory, and wound healing. It also displays vasodilator, hepatoprotective, and antimicrobial effects. Uvaol has inhibitory effects on nitric oxide (NO) release.
  • in vivo

    Uvaol (100-500 μmol/kg; orally administered; 60 min before antigen challenge) can reduce pleural eosinophilic inflammation and IL-5 concentration in a murine pleurisy model induced by ovalbumin[1].

    Animal Model:Male Swiss mice (weighing 25-30 g) with subcutaneous (s.c.) injection on days 0 and 7 with 0.2 mL of a solution containing 50 μg of Ovalbumins (OVA) (HY-W250978) adsorbed to 5 mg of aluminum hydroxide[1].
    Dosage:100 μmol/kg, 200 μmol/kg, 500 μmol/kg (2% DMSO in sterile saline)
    Administration:Oral administration; 60 min before antigen challenge
    Result:Caused a significant decrease in total leukocyte accumulation.
    Induced a significant reduction in the levels of this cytokine.
UVAOL Preparation Products And Raw materials
Raw materials
Preparation Products
UVAOL Suppliers
Global(123)Suppliers
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UVAOL Spectrum
545-46-0, UVAOLRelated Search:
  • Tri-Terpenoids
  • 萜类
  • 中药对照品
  • 抑制剂
  • 天然产物
  • 三萜
  • 标准品 -对照药材
  • 对照品
  • 标准品
  • 植物提取物
  • (3S,4AR,6AR,6BS,8AS,11R,12S,12AS,14AR,14BR)-8A-(羟甲基)-4,4,6A,6B,11,12,14B-七甲基-1,2,3,4,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,14,14A,14B-二十氢苉-3-醇
  • 熊果醇/HPLC
  • 乌发醇(熊果醇)
  • 乌发醇(高根二醇)
  • 熊果醇
  • 乌发醇
  • 545-46-0
  • UVAOL(AS) 10mg
  • antioxidant,allergy,Pleuritis,Inhibitor,Endogenous Metabolite,inflammation,inhibit,eosinophilic,oil,Uvaol
  • "12-Ursen-3-β,28-diol"
  • Urs-12-ene-3,28-diol, (3β)-
  • Ufa
  • Uvaol,Urs-12-ene-3,28-diol
  • UVAOL WITH HPLC
  • urs-12-ene-3beta,28-diol
  • 3BETA,28-DIHYDROXY-URSA-12-EN
  • 3B,28-DIHYDROXY-URSA-12-EN
  • 12-URSEN-3BETA, 28 DIOL
  • 12-URSEN-3B,28-DIOL
  • UVAOL hplc
  • UVAOL(SH)
  • (3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14aR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,11,12,14b-heptamethyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-ol
  • UVAOL
  • URS-12-ENE-3,28-DIOL

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