Description Preparation
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2-CHLOROLEPIDINE

Description Preparation
2-CHLOROLEPIDINE Structure
2-CHLOROLEPIDINE
  • CAS No.634-47-9
  • Chemical Name:2-CHLOROLEPIDINE
  • CBNumber:CB9663910
  • Molecular Formula:C10H8ClN
  • Formula Weight:177.63
  • MOL File:634-47-9.mol
2-CHLOROLEPIDINE Property
  • Melting point 55-58 °C(lit.)
  • Boiling point 296 °C(lit.)
  • Density 1.1810 (rough estimate)
  • refractive index 1.6224 (estimate)
  • Flash point 296°C
  • storage temp. Inert atmosphere,Room Temperature
  • pka 0.98±0.50(Predicted)
  • form powder to crystal
  • color White to Almost white
  • BRN 118333
  • CAS DataBase Reference 634-47-9(CAS DataBase Reference)
  • FDA UNII 2U5ATH9EJR
  • NIST Chemistry Reference Quinoline, 2-chloro-4-methyl-(634-47-9)
  • UNSPSC Code 12352100
  • NACRES NA.22
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P305+P351+P338
2-CHLOROLEPIDINE Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: C0191
  • Product name : 2-Chlorolepidine
  • Purity: min. 98.0 %
  • Packaging: 5G
  • Price: ₹2600
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: C0191
  • Product name : 2-Chlorolepidine
  • Purity: min. 98.0 %
  • Packaging: 25G
  • Price: ₹9000
  • Updated: 2022/05/26
  • Buy: Buy

2-CHLOROLEPIDINE Chemical Properties,Usage,Production

  • Description 4-Methyl-2-chloro-quinoline is an organic intermediate. It has been reported that it can be used to prepare graphite electrodes based on CrO-FeO-PbO and quinoline modified and a modified vermiculite adsorbent for the adsorption and removal of benzene in chemical wastewater.
  • Preparation The mixture of 2-hydroxy-4-methylquinoline and phosphorus oxychloride was heated to 80-85°C. After the solid was completely dissolved, the mixture was poured into ice water, the mixture was extracted with ether, and the ether extract was distilled out of ether. Afterwards, carry out vacuum distillation, collect 132-135 ℃ (0.4kPa) fraction, namely 2-chloro-4-methylquinoline. For further purification, petroleum ether (boiling point 40-50°C) can be used for recrystallization, and the yield is 86%-89%.
  • Chemical Properties white to light yellow crystal powder
  • Uses 2-Chloro-4-methyl-quinoline is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye.
  • Synthesis Reference(s) Journal of the American Chemical Society, 63, p. 2367, 1941 DOI: 10.1021/ja01854a016
    Organic Syntheses, Coll. Vol. 3, p. 194, 1955
2-CHLOROLEPIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-CHLOROLEPIDINE Spectrum
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  • 2-CHLOROLEPIDINE ISO 9001：2015 REACH
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  • OTAVA-BB BB0116110026
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