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2-PYRAZINECARBONYL CHLORIDE

2-PYRAZINECARBONYL CHLORIDE Structure
2-PYRAZINECARBONYL CHLORIDE
  • CAS No.19847-10-0
  • Chemical Name:2-PYRAZINECARBONYL CHLORIDE
  • CBNumber:CB9367638
  • Molecular Formula:C5H3ClN2O
  • Formula Weight:142.54
  • MOL File:19847-10-0.mol
2-PYRAZINECARBONYL CHLORIDE Property
  • Melting point 41°C
  • Boiling point 214.5±20.0 °C(Predicted)
  • Density 1.393±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • pka -2.50±0.10(Predicted)
  • Water Solubility Reacts with water.
  • Sensitive Moisture Sensitive
  • CAS DataBase Reference 19847-10-0(CAS DataBase Reference)
Safety
  • Risk Statements  :34
  • Safety Statements  :26-36/37/39-45
  • RIDADR  :3265
  • HazardClass  :8
  • PackingGroup  :II
  • HS Code  :2933998090
  • NFPA 704:
    0
    3 0
    W
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements H314-H318
  • Precautionary statements P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a

2-PYRAZINECARBONYL CHLORIDE Chemical Properties,Usage,Production

  • Uses 2-Pyrazinecarbonyl Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
2-PYRAZINECARBONYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-PYRAZINECARBONYL CHLORIDE Suppliers
Global(60)Suppliers
  • Supplier：
    career henan chemical co
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  • Country：China
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  • Advantage：58
2-PYRAZINECARBONYL CHLORIDE Spectrum
19847-10-0, 2-PYRAZINECARBONYL CHLORIDERelated Search:
  • Pyridines
  • pharmacetical
  • C5H3ClN2O
  • 2-吡嗪酰氯
  • 吡嗪-2-甲酰氯
  • 2-吡嗪碳酰氯
  • 吡嗪-2-羰基氯
  • 吡嗪-2-甲酰氯, 90+%
  • 吡嗪-2-羰基氯, 90+%
  • 2-吡嗪羰酰氯
  • 19847-10-0
  • pyrazinoyl chloride
  • 2-PYRAZINECARBONYL CHLORIDE ISO 9001：2015 REACH
  • Pyrazine-2-carbonyl chloride, technical, 90%
  • Pyrazine-2-carbonyl chloride, 90+%
  • 2-PYRAZINECARBONYL CHLORIDE: TECH.
  • pyrazinecarbonyl chloride
  • 2-PYRAZINECARBONYL CHLORIDE
  • ASINEX-REAG BAS 07703829
  • TIMTEC-BB SBB010290
  • PYRAZINE-2-CARBOXYLIC ACID CHLORIDE
  • PYRAZINE-2-CARBONYL CHLORIDE

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