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S-acetyl-PEG4-Propargyl

S-acetyl-PEG4-Propargyl Structure
S-acetyl-PEG4-Propargyl
  • CAS No.1422540-88-2
  • Chemical Name:S-acetyl-PEG4-Propargyl
  • CBNumber:CB93163132
  • Molecular Formula:C13H22O5S
  • Formula Weight:290.38
  • MOL File:1422540-88-2.mol
S-acetyl-PEG4-Propargyl Property
  • Boiling point 375.6±37.0 °C(Predicted)
  • Density 1.102±0.06 g/cm3(Predicted)
  • solubility Soluble in DMSO, DCM, DMF
  • form clear liquid
  • color Yellow to Amber to Dark red
Safety
  • HS Code  :2923.90.0100
  • NFPA 704:
    1
    0 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
S-acetyl-PEG4-Propargyl Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: T3698
  • Product name : Acetylthio-PEG4-Alkyne
  • Purity: min. 98.0 %
  • Packaging: 50MG
  • Price: ₹6000
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: T3698
  • Product name : Acetylthio-PEG4-Alkyne
  • Purity: min. 98.0 %
  • Packaging: 250MG
  • Price: ₹19200
  • Updated: 2022/05/26
  • Buy: Buy

S-acetyl-PEG4-Propargyl Chemical Properties,Usage,Production

  • Description S-acetyl-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.
  • Uses S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
S-acetyl-PEG4-Propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
S-acetyl-PEG4-Propargyl Suppliers
Global(31)Suppliers
  • Supplier：
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S-acetyl-PEG4-Propargyl Spectrum
1422540-88-2, S-acetyl-PEG4-PropargylRelated Search:
  • peg
  • 抑制剂
  • 生物医学材料
  • C13H22O5S
  • 化合物 S-ACETYL-PEG4-PROPARGYL
  • 硫-乙酰-四聚乙二醇-丙炔
  • 乙酰基硫基-PEG4-炔
  • 乙酰硫酯-四聚乙二醇-炔
  • 乙酰基巯基-四聚乙二醇-丙炔基
  • 1422540-88-2
  • Acs-PEG4-propargyl
  • S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ethanethioate
  • Ethanethioic Acid S-3,6,9,12-Tetraoxapentadec-14-yn-1-yl Ester
  • Acetylthio-PEG4-Alkyne
  • Reaxys ID: 23366071
  • S-acetyl-PEG4-Alkyne
  • S-acetyl-PEG4-Propargyl

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