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S-acetyl-PEG3-acid

S-acetyl-PEG3-acid Structure
S-acetyl-PEG3-acid
  • CAS No.1421933-33-6
  • Chemical Name:S-acetyl-PEG3-acid
  • CBNumber:CB03062643
  • Molecular Formula:C11H20O6S
  • Formula Weight:280.34
  • MOL File:1421933-33-6.mol
S-acetyl-PEG3-acid Property
  • Boiling point 421.4±40.0 °C(Predicted)
  • Density 1.193±0.06 g/cm3(Predicted)
  • solubility Soluble in Water, DMSO, DCM, DMF
  • pka 4.28±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

S-acetyl-PEG3-acid Chemical Properties,Usage,Production

  • Description S-acetyl-PEG3-acid is a PEG linker containing a sulfur acetyl group and a terminal carboxylic acid. The sulfur acetyl group can be deprotected to produce a thiol moiety. The terminal carboxylic acid can react with primary amines in the presence of EDC or HATU to produce amide bonds. The hydrophilic PEG linker increase the water solubility of the compound in aqueous media.
  • Uses S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
S-acetyl-PEG3-acid Preparation Products And Raw materials
Raw materials
Preparation Products
S-acetyl-PEG3-acid Suppliers
Global(33)Suppliers
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  • Supplier： Borenpharm Co., Ltd
  • Tel：027-65563561
  • Email：sales@borenpharm.com
  • Country：China
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S-acetyl-PEG3-acid Spectrum
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