ChemicalBook > CAS DataBase List > S-acetyl-PEG3-t-butyl ester
S-acetyl-PEG3-t-butyl ester
S-acetyl-PEG3-t-butyl ester
- CAS No.1818294-27-7
- Chemical Name:S-acetyl-PEG3-t-butyl ester
- CBNumber:CB93062646
- Molecular Formula:C15H28O6S
- Formula Weight:336.44
- MOL File:1818294-27-7.mol
S-acetyl-PEG3-t-butyl ester Property
- Boiling point 413.9±35.0 °C(Predicted)
- Density 1.085±0.06 g/cm3(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
S-acetyl-PEG3-t-butyl ester Chemical Properties,Usage,Production
- Description S-acetyl-PEG3-t-butyl ester is a PEG linker containing a sulfur acetyl group and a t-butyl ester. The sulfur acetyl group can be deprotected to form a thiol group. The t-butyl ester can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
- Uses S-acetyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- IC 50 PEGs
- References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
S-acetyl-PEG3-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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- S-acetyl-PEG3-Boc
- S-acetyl-PEG3-t-butyl ester