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Dihydrocholesterol

Dihydrocholesterol Structure
Dihydrocholesterol
  • CAS No.80-97-7
  • Chemical Name:Dihydrocholesterol
  • CBNumber:CB9262856
  • Molecular Formula:C27H48O
  • Formula Weight:388.68
  • MOL File:80-97-7.mol
Dihydrocholesterol Property
  • Melting point 138-142 °C
  • alpha D22 +24.2° (c = 1.3 in chloroform)
  • Boiling point 454.32°C (rough estimate)
  • Density 0.9506 (rough estimate)
  • refractive index 1.5250 (estimate)
  • storage temp. -20°C
  • solubility chloroform: 0.1 g/mL, clear, colorless
  • form A solid
  • pka 15.14±0.70(Predicted)
  • color White to off-white
  • biological source synthetic (organic)
  • Water Solubility Insoluble in water.
  • Merck 14,2200
  • BRN 2418594
  • Stability Stable. Combustible. Incompatible with strong oxidizing agents.
  • LogP 10.065 (est)
  • CAS DataBase Reference 80-97-7(CAS DataBase Reference)
  • EWG's Food Scores 1
  • FDA UNII 8M308U816E
  • NIST Chemistry Reference Cholestanol(80-97-7)
  • EPA Substance Registry System Dihydrocholesterol (80-97-7)
  • UNSPSC Code 41116107
  • NACRES NA.28
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H302-H315-H319-H331-H336-H351-H361d-H372
  • Precautionary statements P261-P281-P305+P351+P338-P311
Dihydrocholesterol Price More Price(7)
  • Brand: Sigma-Aldrich(India)
  • Product number: D6128
  • Product name : 5α-Cholestan-3β-ol
  • Purity: ≥95%
  • Packaging: 10G
  • Price: ₹10121.38
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D6128
  • Product name : 5α-Cholestan-3β-ol
  • Purity: ≥95%
  • Packaging: 25G
  • Price: ₹13953.43
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 8.41513
  • Product name : 5α-Cholestan-3ß-ol
  • Purity: for synthesis
  • Packaging: 5G
  • Price: ₹10330
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 47129
  • Product name : Cholestanol solution
  • Purity: certified reference material, 10?mg/mL in chloroform
  • Packaging: 1ML
  • Price: ₹4934.3
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-L08624-14
  • Product name : 5alpha-Cholestan-3beta-ol, 98%
  • Purity: 
  • Packaging: 25g
  • Price: ₹19700
  • Updated: 2022/05/26
  • Buy: Buy

Dihydrocholesterol Chemical Properties,Usage,Production

  • Description Cholestanol is a cholesterol metabolite formed by oxidation and an intermediate in the biosynthesis of chenodeoxycholic acid . Cholestanol (10 μg/ml) induces apoptosis in cornea and lens epithelial cells and increases the activity of IL-1β converting enzyme (ICE) and CPP32 proteases. Dietary administration of 1% cholestanol to mice increases serum and liver cholestanol levels and leads to corneal opacities and gallstones and in rats it leads to cholestanol deposition in the cerebellum. Cholestanol levels are increased in plasma of patients with cerebrotendinous xanthomatosis (CTX), a disease characterized by a deficiency in the mitochondrial enzyme sterol 27-hydrolylase (CYP27A1) that leads to progressive neurological symptoms.
  • Chemical Properties white powder
  • Uses 5alpha-Cholestan-3beta-ol is used as a standard in lipid analysis using HPLC. It acts as a derivitized steroid compound. It is used in agrochemical, pharmaceutical and dyestuff field .
  • Uses 5α-Cholestan-3β-ol is a carbon stanol formed from biohydrogenation of Cholesterol (C432501) in the gut. Studies have also examined the conversion of 5α-Cholestan-3β-ol catalyzed by 3-β-hydroxysteroid dehydrogenase of rat liver.
  • Definition ChEBI: A cholestanoid that is (5alpha)-cholestane substituted by a beta-hydroxy group at position 3.
  • General Description Cholestanol is a 5α-dihydro derivative of cholesterol. It acts as a marker for cholesterol absorption. Cholestanol is a steroid with 27 carbon atoms.
  • Biochem/physiol Actions 5α-Cholestan-3β-ol is derived from cholesterol by the action of intestinal microorganisms. It is known to induce the formation of gall stones in rabbits in the presence of sodium ions.
  • Purification Methods Purify 5--cholestan-3-ol via acetylation, crystallisation and de-acetylation, then recrystallisation from EtOH or slightly aqueous EtOH, or MeOH. Its solubility is: 0.5% (MeOH) and 1% (EtOH) at 25o. [Mizutani & Whitten J Am Chem Soc 107 3621 1985.] The acetate has m 114-115o from EtOAc/MeOH and, [] D 20 +13o (c 2, CHCl3). [Bruce & Ralls Org Synth Col Vol II 191 1943, Beilstein 6 IV 3577.]
Dihydrocholesterol Preparation Products And Raw materials
Raw materials
Preparation Products
Dihydrocholesterol Suppliers
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Dihydrocholesterol Spectrum
80-97-7, DihydrocholesterolRelated Search:
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  • C27H48O
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  • 标准品对照品】DIHYDROCHOLESTEROL
  • (3S,5S,8R,9S,10S,13R,14S,17R)-10,13-二甲基-17-((R)-6-甲基庚-2-基)十六氢-1H-环戊烷并[A]菲-3-醇
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  • (+)-二氢胆固醇 溶液
  • 80-97-7
  • 5α-Cholestan-3?-ol
  • 5α-Cholestan-3β-ol, 10 mM in DMSO
  • Cholesterol Impurity 18 (Cholestanol)
  • Coumarin Impurity 8
  • Cholestan-3-B-Ol(5A)-(AS)
  • (+)-Dihydrocholesterol
  • (5a)-Cholestan-3b-OL (AS)
  • (3S,5S,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • 5α-Cholestan-3β-ol
  • β-Cholestanol
  • 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • 5A-CHOLESTAN-3B-OL

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