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2,4,7-TRINITRO-9-FLUORENONE

2,4,7-TRINITRO-9-FLUORENONE Structure
2,4,7-TRINITRO-9-FLUORENONE
  • CAS No.129-79-3
  • Chemical Name:2,4,7-TRINITRO-9-FLUORENONE
  • CBNumber:CB9210251
  • Molecular Formula:C13H5N3O7
  • Formula Weight:315.19
  • MOL File:129-79-3.mol
2,4,7-TRINITRO-9-FLUORENONE Property
  • Melting point 176-178°C
  • Boiling point 454.77°C (rough estimate)
  • Density 1.5148 (rough estimate)
  • refractive index 1.5600 (estimate)
  • storage temp. -20°C
  • form powder
  • color white
  • biological source rat
  • Water Solubility water: soluble
  • CAS DataBase Reference 129-79-3(CAS DataBase Reference)
  • EWG's Food Scores 1
  • NCI Dictionary of Cancer Terms TNF
  • FDA UNII B2290YT0WB
  • EPA Substance Registry System 2,4,7-Trinitrofluoren-9-one (129-79-3)
  • UNSPSC Code 12352203
  • NACRES NA.77
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319
  • Precautionary statements P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
2,4,7-TRINITRO-9-FLUORENONE Price More Price(5)
  • Brand: Sigma-Aldrich(India)
  • Product number: T7539
  • Product name : Tumor Necrosis Factor-α from mouse
  • Purity: TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture
  • Packaging: 10μG
  • Price: ₹25818.6
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: T7539
  • Product name : Tumor Necrosis Factor-α from mouse
  • Purity: TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture
  • Packaging: 50μG
  • Price: ₹68786.7
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: T5944
  • Product name : Tumor Necrosis Factor-α from rat
  • Purity: TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture
  • Packaging: 10μG
  • Price: ₹29448.3
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: T5944
  • Product name : Tumor Necrosis Factor-α from rat
  • Purity: TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture
  • Packaging: 50μG
  • Price: ₹68786.7
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: SAB4502982
  • Product name : Anti-TNFA antibody produced in rabbit
  • Purity: affinity isolated antibody
  • Packaging: 100μG
  • Price: ₹50560.5
  • Updated: 2022/06/14
  • Buy: Buy

2,4,7-TRINITRO-9-FLUORENONE Chemical Properties,Usage,Production

  • Uses TNF-α influences the growth and function of both normal and neoplastic cells. TNF-α causes cytolysis or cytostasis of certain transformed cells being synergistic with γ-interferon in its cytotoxicity.
  • Uses Tumor Necrosis Factor-α from mouse, a potent proinflammatory cytokine has been used:
    • to activate MS1 endothelium cells
    • to induce lipolysis in adipocytes
    • to study its effect on liganded and unliganded glucocorticoid receptor (GR) in interleukin (IL)-6 and IL-8 gene regulation
  • General Description Pale yellow needles (from acetic acid or benzene) or yellow powder.
  • Air & Water Reactions Insoluble in water.
  • Reactivity Profile Literature sources indicate that 2,4,7-TRINITRO-9-FLUORENONE is flammable. . Aromatic nitrates range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction.
  • Hazard Suspected carcinogen. Mildly toxic by ingestion. A skin and eye irritant.
  • Fire Hazard Literature sources indicate that 2,4,7-TRINITRO-9-FLUORENONE is flammable.
  • Biochem/physiol Actions The TNFA (tumor necrosis factor α) gene is significantly associated with the regulation of innate and adaptive immune responses. Polymorphism of TNFA gene is known to cause acute motor axonal neuropathy. The cytokine release and gene action is associated with epithelial cells, myeloid cells, endothelial, as well as tumor cells. Tumor cells are known to release TNFA, specifically in response to chemotherapy
  • Safety Profile Suspected carcinogen with experimental tumorigenic data. Mildly toxic by ingestion. Human mutation data reported. A skin and eye irritant. When heated to decomposition it emits hghly toxic fumes of NOx. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS and KETONES.
  • Purification Methods Crystallise it from nitric acid/water (3:1), wash it with water and dry it under vacuum over P2O5, or recrystallise it from dry *benzene. [Beilstein 7 II 410, 7 III 2348, 7 IV 1638.]
2,4,7-TRINITRO-9-FLUORENONE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4,7-TRINITRO-9-FLUORENONE Suppliers
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2,4,7-TRINITRO-9-FLUORENONE Spectrum
129-79-3, 2,4,7-TRINITRO-9-FLUORENONERelated Search:
  • Fluorenes, Flurenones
  • 试剂盒-Elisa试剂盒
  • C13H5N3O7
  • 重组人TNF ALPHA蛋白(HIS TAG)
  • 环己烷中2,4,7-三硝基-9-芴酮
  • 2,4,7-三硝基-9H-芴-9-酮
  • 三硝基芴酮
  • 2,4,7-三硝基-9-芴酮
  • 2，4，7-三硝基芴酮
  • 129-79-3
  • Anti-TNFA antibody produced in rabbit
  • Recombinant Human TNF-alpha Protein, His Tag
  • Recombinant Human TNF-alpha N-His Protein, His Tag
  • Recombinant Human TNFa/TNFSF2/TNF Protein, No Tag
  • Recombinant Human TNF Protein, His Tag
  • 2,4,7-Trinitro-9-fluorenone (wetted with ca. 20% Water) (unit weight on dry weight basis)
  • Tumor Necrosis Factor-α from rat
  • Tumor necrosis factor ligand superfamily member 2
  • Tumor Necrosis Factor-α from mouse
  • mTNF-α
  • TRINITROFLUORENONE
  • 2,4,7-TRINITRO-9-FLUORENONE(WETTEDWITHCA.20%WATER,CONTAINING5GONADRYWEIGHTBASIS)
  • 2,4,7-Trinirofluorenone
  • 2,4,7-Trinitro-9-fluorenone (wetted with ca. 20% Water, containing 5g
  • 2,4,-TRINITRO-9-FLUORENONE (100UG/ML IN TOLUENE)
  • 2,4,7-TRINITRO-9-FLUORENONE
  • 2,4,7-TRINITROFLUORENONE
  • 2，4，7-Trinitrofluoren-9-one
  • LABOTEST-BB LT00645370
  • tnf(ketone)
  • TNF
  • Fluoren-9-one, 2,4,7-trinitro-
  • 9H-Fluoren-9-one, 2,4,7-trinitro-
  • 9-fluorenone,2,4,7-trinitro-
  • 2,4,7-trinitrofluorone
  • 2,4,7-trinitro-fluoren-9-on
  • 2,4,7-Trinitro-9H-fluoren-9-one
  • 2,4,7-trinitro-9h-fluoren-9-on

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