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ARSENAZO III

CAS No.1668-00-4
Chemical Name:ARSENAZO III
CBNumber:CB9208234
Molecular Formula:C22H18As2N4O14S2
Formula Weight:776.37
MOL File:1668-00-4.mol

ARSENAZO III Property

Melting point >320 °C(lit.)
bulk density 850kg/m3
storage temp. Store below +30°C.
solubility ammonium hydroxide: soluble1mg/mL
form Powder
pka -1.25±0.40(Predicted)
color Brown
PH 2.3 (10g/l, H2O, 20℃)
λmax 569-576 nm (buffer pH 10.0)
BRN 5717957
InChIKey UQHVTNUJRKELCE-UHFFFAOYSA-N
SMILES C1=C2C(C(O)=C(N=NC3=CC=CC=C3[As](O)(O)=O)C(S(O)(=O)=O)=C2)=C(O)C(N=NC2=CC=CC=C2[As](O)(O)=O)=C1S(O)(=O)=O
UNSPSC Code 12352103
NACRES NA.47

Safety

Hazard Codes :T,N
Risk Statements :23/25-50/53
Safety Statements :20/21-28-45-60-61
RIDADR :UN 3465 6.1/PG 2
WGK Germany :3
HS Code :2931 90 00
HazardClass :6.1(b)
PackingGroup :III

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H301+H331-H410
Precautionary statements P261-P264-P270-P273-P301+P310-P304+P340+P311

ARSENAZO III Price More Price(11)

Brand: Sigma-Aldrich(India)
Product number: A92775
Product name : Arsenazo III
Purity: calcium-sensitive dye
Packaging: 1G
Price: ₹5310
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: A92775
Product name : Arsenazo III
Purity: calcium-sensitive dye
Packaging: 5G
Price: ₹19830
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: A92775
Product name : Arsenazo III
Purity: calcium-sensitive dye
Packaging: 10G
Price: ₹34300
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich
Product number: 1.10107
Product name : Arsenazo III
Purity: metal indicator
Packaging: 5G
Price: ₹64710
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 1.10107
Product name : Arsenazo III
Purity: metal indicator
Packaging: 5G
Price: ₹64710
Updated: 2022/06/14
Buy: Buy

ARSENAZO III Chemical Properties,Usage,Production

Chemical Properties Dark brown solid
Uses Arsenazo III is usually used in the determination of calcium in serum,has been used to evaluate calcium transport in permeabilized cells,has also been used for the spectrophotometric determination of uranium and thorium.
Uses Arsenazo III reacts with more than 30 metal ions to give coloured complexes. So far it has been utilized for the determination and detection of about 25 metal ions (including 16 rare earth metals). The majority of the analytical procedures are spectrophotometric.
The absorption spectra of the metal complexes of Arsenazo III possess two maxima at about 610 and 665 nm. Since the absorption of the reagent is very low at 665 nm, but is considerable at 610 nm, the extinction of the complexes at 665 nm is utilized for analytical purposes. At this wavelength the molar extinction coefficients of the complexes lie in the range 5 x 104—1.3 x 105. This explains the extremely high analytical sensitivity of the reagent. (Under optimum conditions the sensitivity may reach 0.01 γ/ml.).
The main advantage of Arsenazo III over Arsenazo I lies in the considerably higher stabilities of the complexes of the former. This makes possible the analytical utilization of the reagent in strong mineral acidic media. It gives complexes with tri- and tetravalent metal ions in acidic media where hydrolysis and the consequent formation of polynuclear species do not interfere with the analytically utilized reaction. Those metals whose complexes form only in solutions of higher pH do not interfere with the analytical determination of the metal ions giving complexes in strongly acidic media (thorium, zirconium, uranium, plutonium, neptunium, etc.). This is the reason of the relatively high analytical selectivity of Arsenazo III.
Trace amounts of zirconium can be enriched before determination by coprecipitation with titanium hydroxide. The titanium hydroxide precipitate containing the zirconium content of the sample is dissolved in 6 M hydrochloric acid solution and the zirconium determined photometrically with Arsenazo III. Thousand-fold amounts of titanium do not interfere with the determination of zirconium. The absorption maximum of the zirconium complex of Arsenazo III is at 665 nm.
Uses Spectrophotometric reagent for U, Th, Zr and other metals.Indicator for the precipitation titration of SO4 with Ba.
Biological Activity Arsenazo III is a metallochromic dye. Arsenazo III is used in the determination of calcium in biological samples. It is used to evaluate calcium transport in permeabilized cells. It is also used for the detection of rare earth metals (polyvalent metal ions). Arsenazo III is used for the spectrophotometric determination of uranium and thorium.